| Literature DB >> 15136700 |
D Seripa1, M G Matera, R P D'Andrea, C Gravina, C Masullo, A Daniele, A Bizzarro, M Rinaldi, P Antuono, D R Wekstein, G Dal Forno, V M Fazio.
Abstract
The association of the STH gene polymorphism with Alzheimer disease (AD) is debated. In the analysis of two genetically and diagnostically distinct groups of Alzheimer patients from the USA and Italy, the authors did not find an association with the STH polymorphism. However, the APOE-4-associated risk of AD greatly increased if the STH-G allele was also present. The STH-G allele appears to be a risk modifier for AD.Entities:
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Year: 2004 PMID: 15136700 DOI: 10.1212/01.wnl.0000125693.59817.31
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910