Literature DB >> 15135078

Characterization and promoter analysis of the mouse nestin gene.

Leping Cheng1, Zhigang Jin, Li Liu, Ye Yan, Tingting Li, Xueliang Zhu, Naihe Jing.   

Abstract

The intermediate filament protein nestin is expressed in the neural stem cells of the developing central nervous system (CNS). Promoter analysis revealed that the minimal promoter of the mouse nestin gene resides in the region -11 to +183 of the 5'-non-coding and upstream flanking region, and that two adjacent Sp1-binding sites are necessary for promoter activity. Electrophoretic mobility-shift assays (EMSA) and supershift assays showed that Sp1 and Sp3 proteins selectively bind to the upstream Sp1 site. These results demonstrate an important functionality of Sp1 and Sp3 in regulating the expression of the mouse nestin gene.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15135078     DOI： 10.1016/j.febslet.2004.03.097

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  17 in total

Review 1.  Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis.

Authors:  Toshiyuki Ishiwata; Yoko Matsuda; Zenya Naito
Journal:  World J Gastroenterol       Date:  2011-01-28       Impact factor: 5.742

2.  Nestin expression correlates with nerve and retroperitoneal tissue invasion in pancreatic cancer.

Authors:  Masao Kawamoto; Toshiyuki Ishiwata; Kazumitsu Cho; Eiji Uchida; Murray Korc; Zenya Naito; Takashi Tajiri
Journal:  Hum Pathol       Date:  2008-09-16       Impact factor: 3.466

Review 3.  Genetic dissection of neural circuits and behavior in Mus musculus.

Authors:  Robbert Havekes; Ted Abel
Journal:  Adv Genet       Date:  2009       Impact factor: 1.944

4.  Comparing stemness gene expression between stem cell subpopulations from peripheral blood and adipose tissue.

Authors:  Maria Teresa González-Garza; Delia E Cruz-Vega; Alejandro Cárdenas-Lopez; Rosa Maria de la Rosa; Jorge E Moreno-Cuevas
Journal:  Am J Stem Cells       Date:  2018-06-01

5.  Cell aggregation-induced FGF8 elevation is essential for P19 cell neural differentiation.

Authors:  Chen Wang; Caihong Xia; Wei Bian; Li Liu; Wei Lin; Ye-Guang Chen; Siew-Lan Ang; Naihe Jing
Journal:  Mol Biol Cell       Date:  2006-04-26       Impact factor: 4.138

6.  Na⁺/K⁺-ATPase β2-subunit (AMOG) expression abrogates invasion of glioblastoma-derived brain tumor-initiating cells.

Authors:  Matthew Z Sun; Joseph M Kim; Michael C Oh; Michael Safaee; Gurvinder Kaur; Aaron J Clark; Orin Bloch; Michael E Ivan; Rajwant Kaur; Taemin Oh; Shaun D Fouse; Joanna J Phillips; Mitchel S Berger; Andrew T Parsa
Journal:  Neuro Oncol       Date:  2013-07-25       Impact factor: 12.300

7.  Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development.

Authors:  Zhigang Jin; Li Liu; Wei Bian; Yongfeng Chen; Guoliang Xu; Leping Cheng; Naihe Jing
Journal:  J Biol Chem       Date:  2009-01-15       Impact factor: 5.157

8.  p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.

Authors:  Darjus F Tschaharganeh; Wen Xue; Diego F Calvisi; Matthias Evert; Tatyana V Michurina; Lukas E Dow; Ana Banito; Sarah F Katz; Edward R Kastenhuber; Susann Weissmueller; Chun-Hao Huang; Andre Lechel; Jesper B Andersen; David Capper; Lars Zender; Thomas Longerich; Grigori Enikolopov; Scott W Lowe
Journal:  Cell       Date:  2014-07-31       Impact factor: 41.582

9.  Maximal Expression of the Evolutionarily Conserved Slit2 Gene Promoter Requires Sp1.

Authors:  Jacquelyn Saunders; D Roonalika Wisidagama; Travis Morford; Cindy S Malone
Journal:  Cell Mol Neurobiol       Date:  2015-10-11       Impact factor: 5.046

10.  Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation.

Authors:  G Gopisetty; J Xu; D Sampath; H Colman; V K Puduvalli
Journal:  Oncogene       Date:  2012-09-03       Impact factor: 9.867
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.