Literature DB >> 15127805

Rapid HPLC method for the determination of paclitaxel in pharmaceutical forms without separation.

Irinel Badea1, Dana Ciutaru, Lelia Lazar, Daniela Nicolescu, Aurel Tudose.   

Abstract

A HPLC method has been developed for the in-process determination of the paclitaxel from dosage pharmaceutical forms. This method ensures the rapid determination of paclitaxel in the presence of polyoxyl castor oil--the main constituent of paclitaxel's clinical formulation vehicle. The method is simple and rapid and does not require any preliminary treatment of the sample. The method was fully validated.

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Year:  2004        PMID: 15127805     DOI: 10.1016/s0731-7085(03)00628-9

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  4 in total

1.  Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel.

Authors:  Sushrut Marathe; Gauri Shadambikar; Tabish Mehraj; Suresh P Sulochana; Narendar Dudhipala; Soumyajit Majumdar
Journal:  Pharmaceutics       Date:  2022-05-11       Impact factor: 6.525

2.  Rapid and sensitive liquid chromatographic method for determination of Paclitaxel from parenteral formulation and nanoparticles.

Authors:  S Kollipara; G Bende; R N Saha
Journal:  Indian J Pharm Sci       Date:  2010-07       Impact factor: 0.975

3.  Validated HPLC Method for the Determination of Paclitaxel-related Substances in an Intravenous Emulsion Loaded with a Paclitaxel-Cholesterol Complex.

Authors:  X J Xia; J Peng; P X Zhang; D J Jin; Y L Liu
Journal:  Indian J Pharm Sci       Date:  2013-11       Impact factor: 0.975

4.  Development and Validation of a Rapid RP-HPLC-DAD Analysis Method for the Simultaneous Quantitation of Paclitaxel and Lapatinib in a Polymeric Micelle Formulation.

Authors:  Ebrahim Saadat; Fatemeh Ravar; Pouya Dehghankelishadi; Farid A Dorkoosh
Journal:  Sci Pharm       Date:  2015-12-29
  4 in total

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