BACKGROUND CONTEXT: The New Zealand White rabbit model for posterolateral lumbar fusion is commonly used for spinal fusion research. However, the high rate of animal morbidity and mortality associated with the model makes experimentation inefficient and can lead to faulty data analysis. Operative complications are in part the result of inadequate knowledge of normal rabbit lumbar spine anatomy. PURPOSE: To describe the lumbar spine anatomy of the New Zealand White rabbit as it pertains to the surgical technique of posterolateral intertransverse arthrodesis. STUDY DESIGN/ SETTING: This is a descriptive anatomical study of the lumbar spine (and related structures) of the New Zealand White rabbit spinal fusion model. The study was performed at a university research facility. METHODS: The lumbar spine and associated soft tissue structures of 16 previously sacrificed, skeletally mature New Zealand White rabbits were dissected and examined. RESULTS: The musculoskeletal and neurologic structures relevant to posterolateral lumbar fusion in the New Zealand White rabbit are described. CONCLUSIONS: Specific knowledge of rabbit lumbar spine anatomy allows the researcher to more rapidly acquire expertise in the surgical technique of posterolateral arthrodesis. Improved technical execution of the procedure should lower the complication rate, reduce the costs of experimentation and lead to more reliable and reproducible results.
BACKGROUND CONTEXT: The New Zealand White rabbit model for posterolateral lumbar fusion is commonly used for spinal fusion research. However, the high rate of animal morbidity and mortality associated with the model makes experimentation inefficient and can lead to faulty data analysis. Operative complications are in part the result of inadequate knowledge of normal rabbit lumbar spine anatomy. PURPOSE: To describe the lumbar spine anatomy of the New Zealand White rabbit as it pertains to the surgical technique of posterolateral intertransverse arthrodesis. STUDY DESIGN/ SETTING: This is a descriptive anatomical study of the lumbar spine (and related structures) of the New Zealand White rabbit spinal fusion model. The study was performed at a university research facility. METHODS: The lumbar spine and associated soft tissue structures of 16 previously sacrificed, skeletally mature New Zealand White rabbits were dissected and examined. RESULTS: The musculoskeletal and neurologic structures relevant to posterolateral lumbar fusion in the New Zealand White rabbit are described. CONCLUSIONS: Specific knowledge of rabbit lumbar spine anatomy allows the researcher to more rapidly acquire expertise in the surgical technique of posterolateral arthrodesis. Improved technical execution of the procedure should lower the complication rate, reduce the costs of experimentation and lead to more reliable and reproducible results.
Authors: William R Walsh; Rema A Oliver; Gary Gage; Yan Yu; David Bell; Jeremy Bellemore; Huston Davis Adkisson Journal: Tissue Eng Part A Date: 2010-10-08 Impact factor: 3.845
Authors: James D Crowley; Rema A Oliver; Michael J Dan; Daniel J Wills; John W Rawlinson; Rebekah A Crasto; James M O'Connor; Gregory J Mitchell; Christopher J Tan; William R Walsh Journal: JOR Spine Date: 2020-12-23