Literature DB >> 1512552

Inhibition of proliferation of normal and transformed neural cells by blood group-related oligosaccharides.

F F Santos-Benito1, A Fernández-Mayoralas, M Martín-Lomas, M Nieto-Sampedro.   

Abstract

A synthetic tetrasaccharide structurally related to blood groups and selectin ligands inhibited division of astrocytes, gliomas, and neuroblastomas at micromolar concentrations. The compound was cytostatic for primary astrocytes in culture, but cytotoxic for fast proliferating cell lines.

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Year:  1992        PMID: 1512552      PMCID: PMC2119348          DOI: 10.1084/jem.176.3.915

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  13 in total

1.  Sweetening the selectin pot.

Authors:  M Siegelman
Journal:  Curr Biol       Date:  1991-04       Impact factor: 10.834

2.  Synthesis of oligosaccharide inhibitors of neural cell division.

Authors:  F F Santos-Benito; M Nieto-Sampedro; A Fernández-Mayoralas; M Martín-Lomas
Journal:  Carbohydr Res       Date:  1992-06-04       Impact factor: 2.104

3.  Differing reactions of monoclonal anti-A antibodies with oligosaccharides related to blood group A.

Authors:  H C Gooi; E F Hounsell; J K Picard; A D Lowe; D Voak; E S Lennox; T Feizi
Journal:  J Biol Chem       Date:  1985-10-25       Impact factor: 5.157

4.  Distribution of anti-Leu-7, anti-Leu-11a and anti-Leu-M1 immunoreactivity in the brain of the adult rat.

Authors:  G Reifenberger; J K Mai; S Krajewski; W Wechsler
Journal:  Cell Tissue Res       Date:  1987-05       Impact factor: 5.249

5.  Cell adhesion. Sticky sugars for selectins.

Authors:  T A Springer; L A Lasky
Journal:  Nature       Date:  1991-01-17       Impact factor: 49.962

6.  Purification of an active EGF receptor kinase with monoclonal antireceptor antibodies.

Authors:  Y Yarden; I Harari; J Schlessinger
Journal:  J Biol Chem       Date:  1985-01-10       Impact factor: 5.157

7.  An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide.

Authors:  K H Jones; J A Senft
Journal:  J Histochem Cytochem       Date:  1985-01       Impact factor: 2.479

8.  Sialylated Lewis antigen detected in the sera of cancer patients.

Authors:  T Iguro; A Wakisaka; P I Terasaki; M Hirota; N Suyama; K Fukushima; D Chia; M Kawahara
Journal:  Lancet       Date:  1984-10-06       Impact factor: 79.321

9.  Characterization of sialosylated Lewisx as a new tumor-associated antigen.

Authors:  K Fukushima; M Hirota; P I Terasaki; A Wakisaka; H Togashi; D Chia; N Suyama; Y Fukushi; E Nudelman; S Hakomori
Journal:  Cancer Res       Date:  1984-11       Impact factor: 12.701

10.  Antigenic and functional characterization of a rat central nervous system-derived cell line immortalized by a retroviral vector.

Authors:  H M Geller; M Dubois-Dalcq
Journal:  J Cell Biol       Date:  1988-11       Impact factor: 10.539

View more
  5 in total

1.  Glioma growth inhibition by neurostatin and O-But GD1b.

Authors:  Beatriz Valle-Argos; Diego Gómez-Nicola; Manuel Nieto-Sampedro
Journal:  Neuro Oncol       Date:  2010-07-08       Impact factor: 12.300

2.  Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.

Authors:  Manuel Nieto-Sampedro; Beatriz Valle-Argos; Diego Gómez-Nicola; Alfonso Fernández-Mayoralas; Manuel Nieto-Díaz
Journal:  Clin Med Insights Oncol       Date:  2011-09-21

3.  Solution conformation and dynamics of a tetrasaccharide related to the Lewis(x) antigen deduced by NMR relaxation measurements.

Authors:  A Poveda; J L Asensio; M Martín-Pastor; J Jiménez-Barbero
Journal:  J Biomol NMR       Date:  1997-07       Impact factor: 2.835

4.  Cell type-dependent alterations of binding of synthetic blood group antigen-related oligosaccharides in lung cancer.

Authors:  K Kayser; N V Bovin; T V Zemlyanukhina; S Donaldo-Jacinto; J Koopmann; H J Gabius
Journal:  Glycoconj J       Date:  1994-08       Impact factor: 2.916

Review 5.  [Protein-carbohydrate recognition. Foundation and medical application with illustrations of tumor lectin studies].

Authors:  H J Gabius; K Kayser; S Gabius
Journal:  Naturwissenschaften       Date:  1995-12
  5 in total

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