Literature DB >> 15124627

New inhibitors targeting bacterial RNA polymerase.

Seth A Darst1.   

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Year:  2004        PMID: 15124627     DOI: 10.1016/j.tibs.2004.02.005

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


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  16 in total

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2.  Involvement of the beta subunit of RNA polymerase in resistance to streptolydigin and streptovaricin in the producer organisms Streptomyces lydicus and Streptomyces spectabilis.

Authors:  Marina Sánchez-Hidalgo; Luz Elena Núñez; Carmen Méndez; José A Salas
Journal:  Antimicrob Agents Chemother       Date:  2010-02-22       Impact factor: 5.191

3.  Molecular genetic and structural modeling studies of Staphylococcus aureus RNA polymerase and the fitness of rifampin resistance genotypes in relation to clinical prevalence.

Authors:  A J O'Neill; T Huovinen; C W G Fishwick; I Chopra
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

4.  pocketZebra: a web-server for automated selection and classification of subfamily-specific binding sites by bioinformatic analysis of diverse protein families.

Authors:  Dmitry Suplatov; Eugeny Kirilin; Mikhail Arbatsky; Vakil Takhaveev; Vytas Svedas
Journal:  Nucleic Acids Res       Date:  2014-05-22       Impact factor: 16.971

5.  New insights into the bacterial RNA polymerase inhibitor CBR703 as a starting point for optimization as an anti-infective agent.

Authors:  Weixing Zhu; Jörg Haupenthal; Matthias Groh; Michelle Fountain; Rolf W Hartmann
Journal:  Antimicrob Agents Chemother       Date:  2014-05-12       Impact factor: 5.191

6.  Mechanism of transcription initiation at an activator-dependent promoter defined by single-molecule observation.

Authors:  Larry J Friedman; Jeff Gelles
Journal:  Cell       Date:  2012-02-17       Impact factor: 41.582

7.  Chemical synthesis enables biochemical and antibacterial evaluation of streptolydigin antibiotics.

Authors:  Sergey V Pronin; Anthony Martinez; Konstantin Kuznedelov; Konstantin Severinov; Howard A Shuman; Sergey A Kozmin
Journal:  J Am Chem Soc       Date:  2011-07-20       Impact factor: 15.419

8.  Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase.

Authors:  Elizabeth A Campbell; Olga Pavlova; Nikolay Zenkin; Fred Leon; Herbert Irschik; Rolf Jansen; Konstantin Severinov; Seth A Darst
Journal:  EMBO J       Date:  2005-02-03       Impact factor: 11.598

Review 9.  Genome-guided discovery of diverse natural products from Burkholderia sp.

Authors:  Xiangyang Liu; Yi-Qiang Cheng
Journal:  J Ind Microbiol Biotechnol       Date:  2013-11-09       Impact factor: 3.346

10.  The RNA polymerase "switch region" is a target for inhibitors.

Authors:  Jayanta Mukhopadhyay; Kalyan Das; Sajida Ismail; David Koppstein; Minyoung Jang; Brian Hudson; Stefan Sarafianos; Steven Tuske; Jay Patel; Rolf Jansen; Herbert Irschik; Eddy Arnold; Richard H Ebright
Journal:  Cell       Date:  2008-10-17       Impact factor: 41.582

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