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Literature DB >> 15120089

Molecular evolution: introns fall into place.

Abstract

The evolutionary origin of spliceosomal introns remains elusive. The startling success of a new way of predicting intron sites suggests that the splicing machinery determines where introns are added to genes.

Mesh：

Substances：
RNA Splice Sites

Year: 2004 PMID： 15120089 DOI： 10.1016/j.cub.2004.04.024

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

14 in total

Review 1. Worm genomes hold the smoking guns of intron gain.

Authors: John M Logsdon
Journal: Proc Natl Acad Sci U S A Date: 2004-07-26 Impact factor: 11.205

2. Complex early genes.

Authors: Scott W Roy; Walter Gilbert
Journal: Proc Natl Acad Sci U S A Date: 2005-02-01 Impact factor: 11.205

3. Spliceosomal introns in the deep-branching eukaryote Trichomonas vaginalis.

Authors: Stepánka Vanácová; Weihong Yan; Jane M Carlton; Patricia J Johnson
Journal: Proc Natl Acad Sci U S A Date: 2005-03-11 Impact factor: 11.205

4. Cryptic splice site usage in exon 7 of the human fibrinogen Bbeta-chain gene is regulated by a naturally silent SF2/ASF binding site within this exon.

Authors: Silvia Spena; Maria Luisa Tenchini; Emanuele Buratti
Journal: RNA Date: 2006-04-12 Impact factor: 4.942

Molecular evolution: introns fall into place.

Review 1. Worm genomes hold the smoking guns of intron gain.

2. Complex early genes.

3. Spliceosomal introns in the deep-branching eukaryote Trichomonas vaginalis.

4. Cryptic splice site usage in exon 7 of the human fibrinogen Bbeta-chain gene is regulated by a naturally silent SF2/ASF binding site within this exon.

5. Phylogenetic distribution of intron positions in alpha-amylase genes of bilateria suggests numerous gains and losses.

6. Cryptic splice sites and split genes.

7. Phase distribution of spliceosomal introns: implications for intron origin.

Review 8. Defective splicing, disease and therapy: searching for master checkpoints in exon definition.

9. Synonymous codon usage bias is correlative to intron number and shows disequilibrium among exons in plants.

10. Large-scale trends in the evolution of gene structures within 11 animal genomes.