Literature DB >> 15120085

Nodal signaling: CrypticLefty mechanism of antagonism decoded.

William W Branford1, H Joseph Yost.   

Abstract

The secreted TGFbeta factor Lefty antagonizes Nodal signaling during vertebrate embryogenesis, but how it does so has been a mystery. Recent analyses have elucidated the molecular mechanisms underlying this function of Lefty.

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Year:  2004        PMID： 15120085     DOI： 10.1016/j.cub.2004.04.020

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  6 in total

1.  FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development.

Authors:  Aaron B Steiner; Mark J Engleka; Qun Lu; Eileen C Piwarzyk; Sergey Yaklichkin; Julie L Lefebvre; James W Walters; Liliam Pineda-Salgado; Patricia A Labosky; Daniel S Kessler
Journal:  Development       Date:  2006-11-08       Impact factor: 6.868

2.  Nodal and lefty signaling regulates the growth of pancreatic cells.

Authors:  You-Qing Zhang; Lori Sterling; Aleksandr Stotland; Hong Hua; Marcie Kritzik; Nora Sarvetnick
Journal:  Dev Dyn       Date:  2008-05       Impact factor: 3.780

3.  Cripto binds transforming growth factor beta (TGF-beta) and inhibits TGF-beta signaling.

Authors:  Peter C Gray; Gidi Shani; Kevin Aung; Jonathan Kelber; Wylie Vale
Journal:  Mol Cell Biol       Date:  2006-10-09       Impact factor: 4.272

Review 4.  Modelling from the experimental developmental biologists viewpoint.

Authors:  Andrew D Economou; Jeremy B A Green
Journal:  Semin Cell Dev Biol       Date:  2014-07-12       Impact factor: 7.727

5.  Nodal signalling in Xenopus: the role of Xnr5 in left/right asymmetry and heart development.

Authors:  Emmanuel Tadjuidje; Matthew Kofron; Adnan Mir; Christopher Wylie; Janet Heasman; Sang-Wook Cha
Journal:  Open Biol       Date:  2016-08       Impact factor: 6.411

6.  Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.

Authors:  Shannon E Powers; Kenichiro Taniguchi; Weiwei Yen; Tiffany A Melhuish; Jun Shen; Christopher A Walsh; Ann E Sutherland; David Wotton
Journal:  Development       Date:  2010-01       Impact factor: 6.868
  6 in total

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