Literature DB >> 15113463

Prevention of pulmonary embolism by combined modalities of thromboprophylaxis and intensive surveillance protocol.

Mukesh Misra1, Ben Roitberg, Koji Ebersole, Fady T Charbel.   

Abstract

OBJECTIVE: Deep vein thrombosis (DVT) is a known complication in neurosurgical patients. The protocols for the prevention of DVT and pulmonary embolism (PE) are not applied universally. Our goal was to review the incidence of DVT and PE in neurosurgical intensive care units (NSICUs) and to compare it with the incidence of DVT and PE in other intensive care units (ICUs) in the same hospital.
METHODS: We retrospectively reviewed 5327 consecutive admissions in all intensive care units at the University of Illinois Hospital between July 2001 and June 2002. The NSICU had 1094 admissions, and all other ICUs combined had 4233 admissions. In our NSICU, every patient was administered DVT prophylaxis in the form of subcutaneous heparin and a sequential compression device if these treatments were not contraindicated. Lower-extremity venous Doppler ultrasonography was performed twice weekly in all NSICU patients. There was no routine use of DVT prophylaxis in the other ICUs, and no other ICUs performed routine lower-extremity venous Doppler ultrasonography. We compared the incidence of DVT and PE in the NSICU and the combined population of other adult ICUs.
RESULTS: PE was diagnosed in 1 (0.09%) of 1094 patients in the NSICU and in 45 (1.06%) of 4233 patients in all other ICUs (P < 0.0001, Z = 5.34). DVT was diagnosed in 28 patients (2.55%) in the NSICU and in 238 patients (5.62%) in all other ICUs (P < 0.001, Z = 4.32). These values suggest a statistically significant difference in the incidence of DVT and PE in the NSICU compared with all other ICUs.
CONCLUSION: We conclude that there was a significantly lower incidence of DVT and PE in the NSICU than in all other ICUs at our institution. DVT prophylaxis and twice-weekly lower-extremity venous Doppler screening in the NSICU have been found to be beneficial in decreasing the incidence of DVT and particularly effective in preventing PE.

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Year:  2004        PMID: 15113463     DOI: 10.1227/01.neu.0000119352.71531.29

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  6 in total

1.  Risk factors for venous thromboembolism in patients undergoing craniotomy for neoplastic disease.

Authors:  Kristopher T Kimmell; Kevin A Walter
Journal:  J Neurooncol       Date:  2014-08-23       Impact factor: 4.130

2.  The incidence of deep vein thrombosis detected by routine surveillance ultrasound in neurosurgery patients receiving dual modality prophylaxis.

Authors:  Patricia C Henwood; Thomas M Kennedy; Lynda Thomson; Taki Galanis; George L Tzanis; Geno J Merli; Walter K Kraft
Journal:  J Thromb Thrombolysis       Date:  2011-08       Impact factor: 2.300

3.  Impact of screening versus symptomatic measurement of deep vein thrombosis in a national quality improvement registry.

Authors:  Randall R De Martino; Adam W Beck; Matthew S Edwards; Matthew A Corriere; Jessica B Wallaert; David H Stone; Jack L Cronenwett; Philip P Goodney
Journal:  J Vasc Surg       Date:  2012-07-24       Impact factor: 4.268

Review 4.  Prophylaxis for venous thrombo-embolism in neurocritical care: a critical appraisal.

Authors:  Ahmed M Raslan; Jeremy D Fields; Anish Bhardwaj
Journal:  Neurocrit Care       Date:  2010-04       Impact factor: 3.210

5.  Surveillance Ultrasound in the Neuro Intensive Care Unit: Time to Deep Vein Thrombosis Diagnosis.

Authors:  Kristi L Hargrove; Colleen A Barthol; Stefan Allen; Crystal Franco-Martinez
Journal:  Neurocrit Care       Date:  2019-06       Impact factor: 3.210

Review 6.  Ancillary ICU Care in Patients with Acute Brain Insults.

Authors:  Kapil Dev Chhabra; Mandeep Singh
Journal:  Indian J Crit Care Med       Date:  2019-06
  6 in total

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