| Literature DB >> 15112655 |
Jie Yang1, Dirk Hoffmeister, Lesley Liu, Xun Fu, Jon S Thorson.
Abstract
glycorandomization is a chemoenzymatic strategy that overcomes the limitations in natural product derivatization associated with both solely chemistry-based approaches or in vivo engineering. In this article we present the basic strategies for glycorandomization development as a next-generation tool in drug discovery.Mesh:
Substances:
Year: 2004 PMID: 15112655 DOI: 10.1016/j.bmc.2003.12.046
Source DB: PubMed Journal: Bioorg Med Chem ISSN: 0968-0896 Impact factor: 3.641