Literature DB >> 15112655

Natural product glycorandomization.

Jie Yang1, Dirk Hoffmeister, Lesley Liu, Xun Fu, Jon S Thorson.   

Abstract

glycorandomization is a chemoenzymatic strategy that overcomes the limitations in natural product derivatization associated with both solely chemistry-based approaches or in vivo engineering. In this article we present the basic strategies for glycorandomization development as a next-generation tool in drug discovery.

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Year:  2004        PMID: 15112655     DOI: 10.1016/j.bmc.2003.12.046

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  11 in total

Review 1.  The structural biology of enzymes involved in natural product glycosylation.

Authors:  Shanteri Singh; George N Phillips; Jon S Thorson
Journal:  Nat Prod Rep       Date:  2012-06-12       Impact factor: 13.423

Review 2.  Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?

Authors:  Richard H Baltz
Journal:  J Ind Microbiol Biotechnol       Date:  2006-01-18       Impact factor: 3.346

Review 3.  Combinatorial biosynthesis--potential and problems.

Authors:  Heinz G Floss
Journal:  J Biotechnol       Date:  2006-01-18       Impact factor: 3.307

4.  Structural insights into the catalytic mechanism of bacterial guanosine-diphospho-D-mannose pyrophosphorylase and its regulation by divalent ions.

Authors:  Marie-Cécile Pelissier; Scott A Lesley; Peter Kuhn; Yves Bourne
Journal:  J Biol Chem       Date:  2010-06-23       Impact factor: 5.157

5.  Production of a novel quercetin glycoside through metabolic engineering of Escherichia coli.

Authors:  Jeong-A Yoon; Bong-Gyu Kim; Woo Ju Lee; Yoongho Lim; Youhoon Chong; Joong-Hoon Ahn
Journal:  Appl Environ Microbiol       Date:  2012-04-06       Impact factor: 4.792

6.  Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization.

Authors:  Joseph M Langenhan; Noël R Peters; Ilia A Guzei; F Michael Hoffmann; Jon S Thorson
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-16       Impact factor: 11.205

Review 7.  Natural-product sugar biosynthesis and enzymatic glycodiversification.

Authors:  Christopher J Thibodeaux; Charles E Melançon; Hung-wen Liu
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

8.  One-pot multienzyme (OPME) systems for chemoenzymatic synthesis of carbohydrates.

Authors:  Hai Yu; Xi Chen
Journal:  Org Biomol Chem       Date:  2016-03-14       Impact factor: 3.876

9.  Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions.

Authors:  Richard W Gantt; Pauline Peltier-Pain; William J Cournoyer; Jon S Thorson
Journal:  Nat Chem Biol       Date:  2011-08-21       Impact factor: 15.040

10.  Metabolically engineered Escherichia coli for efficient production of glycosylated natural products.

Authors:  Salvador Peirú; Eduardo Rodríguez; Hugo G Menzella; John R Carney; Hugo Gramajo
Journal:  Microb Biotechnol       Date:  2008-08-04       Impact factor: 5.813

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