| Literature DB >> 15109679 |
Steven D Linton1, Teresa Aja, Peter R Allegrini, Thomas L Deckwerth, Jose-Luis Diaz, Bastian Hengerer, Julia Herrmann, Kathy G Jahangiri, Joerg Kallen, Donald S Karanewsky, Steven P Meduna, Kip Nalley, Edward D Robinson, Silvio Roggo, Giorgio Rovelli, Andre Sauter, Robert O Sayers, Albert Schmitz, Robert Smidt, Robert J Ternansky, Kevin J Tomaselli, Brett R Ullman, Christoph Wiessner, Joe C Wu.
Abstract
Structural modifications were made to a previously described acyl dipeptide caspase inhibitor, leading to the oxamyl dipeptide series. Subsequent SAR studies directed toward the warhead, P2, and P4 regions of this novel peptidomimetic are described herein.Entities:
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Year: 2004 PMID： 15109679 DOI： 10.1016/j.bmcl.2003.12.106
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823