| Literature DB >> 15109632 |
Akihiko Hatano1, Seiji Makita, Masayuki Kirihara.
Abstract
A redox-active nucleobase analogue of a nucleotide was synthesized and incorporated into DNA using phosphoramidite chemistry. An analogue-containing oligonucleotide in the absence of a reducing reagent formed a stable duplex with a substantially higher melting temperature compared to that of a standard DNA duplex of the same length.Entities:
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Year: 2004 PMID： 15109632 DOI： 10.1016/j.bmcl.2004.03.015
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823