Literature DB >> 15107974

Maternal brain death: medical, ethical and legal issues.

Alan Lane1, Andrew Westbrook, Deirdre Grady, Rory O'Connor, Timothy J Counihan, Brian Marsh, John G Laffey.   

Abstract

CASE
PRESENTATION: We present the case of a pregnant woman who experienced a cerebral venous sinus thrombosis resulting in brain death at 13 weeks gestation. We discuss the management of the mother and foetus following this tragic event. We also discuss the complex medical, legal and ethical issues that arose following maternal brain death. The central question is whether continuing maternal organ supportive measures in an attempt to prolong gestation to attain foetal viability is appropriate, or whether it constitutes futile care. DISCUSSION: Successful maintenance of maternal brain somatic function to facilitate foetal maturation in utero has been reported. While the gestational age of the foetus is central to resolving this issue, there is no clear upper physiological limit to the prolongation of somatic function following brain death. Furthermore, medical experience regarding prolonged somatic support is limited. Finally, the legal rights conferred on the foetus may vary significantly depending on the jurisdiction in which the maternal brain death occurs and may have important implications.
CONCLUSIONS: A consensus building approach, involving the family, is essential to resolving these potentially conflicting issues.

Entities:  

Keywords:  Death and Euthanasia; Genetics and Reproduction

Mesh:

Year:  2004        PMID: 15107974     DOI: 10.1007/s00134-004-2305-6

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  7 in total

Review 1.  Cerebral arteriovenous malformation in pregnancy: presentation and neurologic, obstetric, and ethical significance.

Authors:  J J Finnerty; C A Chisholm; H Chapple; I S Login; J V Pinkerton
Journal:  Am J Obstet Gynecol       Date:  1999-08       Impact factor: 8.661

2.  Extended somatic support for pregnant women after brain death.

Authors:  David J Powner; Ira M Bernstein
Journal:  Crit Care Med       Date:  2003-04       Impact factor: 7.598

3.  Maternal brain death during pregnancy. Medical and ethical issues.

Authors:  D R Field; E A Gates; R K Creasy; A R Jonsen; R K Laros
Journal:  JAMA       Date:  1988-08-12       Impact factor: 56.272

4.  Brain death worldwide: accepted fact but no global consensus in diagnostic criteria.

Authors:  Eelco F M Wijdicks
Journal:  Neurology       Date:  2002-01-08       Impact factor: 9.910

Review 5.  Irreversible maternal brain injury during pregnancy: a case report and review of the literature.

Authors:  D M Feldman; A F Borgida; J F Rodis; W A Campbell
Journal:  Obstet Gynecol Surv       Date:  2000-11       Impact factor: 2.347

6.  Should a brain-dead pregnant woman carry her child to full term? The case of the "Erlanger baby"

Authors:  Christoph Anstötz
Journal:  Bioethics       Date:  1993-07       Impact factor: 1.898

7.  Maternal brain death and prolonged fetal survival.

Authors:  I M Bernstein; M Watson; G M Simmons; P M Catalano; G Davis; R Collins
Journal:  Obstet Gynecol       Date:  1989-09       Impact factor: 7.661

  7 in total
  5 in total

Review 1.  Maternal brain death--an Irish perspective.

Authors:  R Farragher; B Marsh; J G Laffey
Journal:  Ir J Med Sci       Date:  2005 Oct-Dec       Impact factor: 1.568

Review 2.  Maternal brain death and somatic support.

Authors:  Rachel A Farragher; John G Laffey
Journal:  Neurocrit Care       Date:  2005       Impact factor: 3.210

Review 3.  Intracranial haemorrhage in pregnancy.

Authors:  Jacob M Fairhall; Marcus A Stoodley
Journal:  Obstet Med       Date:  2009-11-30

4.  When Death Is Not the End: Continuing Somatic Care during Postmortem Pregnancy.

Authors:  Jennifer J Barr
Journal:  Linacre Q       Date:  2019-09-25

Review 5.  One life ends, another begins: Management of a brain-dead pregnant mother-A systematic review-.

Authors:  Majid Esmaeilzadeh; Christine Dictus; Elham Kayvanpour; Farbod Sedaghat-Hamedani; Michael Eichbaum; Stefan Hofer; Guido Engelmann; Hamidreza Fonouni; Mohammad Golriz; Jan Schmidt; Andreas Unterberg; Arianeb Mehrabi; Rezvan Ahmadi
Journal:  BMC Med       Date:  2010-11-18       Impact factor: 8.775

  5 in total

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