Literature DB >> 15102822

Proinflammatory cytokine expression in the early phase of Trypanosoma brucei rhodesiense infection in vervet monkeys (Cercopithecus aethiops).

Naomi Maina1, Joseph Maina Ngotho, Tom Were, John Kibuthu Thuita, David Mumo Mwangangi, John Maina Kagira, Joseph Mathu Ndung'u, Jeremy Sternberg.   

Abstract

A vervet monkey model of trypanosomiasis was used to study inflammatory cytokine responses in serum and cerebrospinal fluid (CSF). Gamma interferon levels were transiently up-regulated in serum between days 6 and 8 of infection, followed by a sustained up-regulation of tumor necrosis factor alpha (TNF-alpha) and soluble TNF receptor 1. At no time were these cytokines detectable in the CSF.

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Year:  2004        PMID： 15102822      PMCID： PMC387871          DOI： 10.1128/IAI.72.5.3063-3065.2004

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  11 in total

1.  Plasma nitrate and interferon-gamma in Trypanosoma brucei rhodesiense infections: evidence that nitric oxide production is induced during both early blood-stage and late meningoencephalitic-stage infections.

Authors:  L MacLean; M Odiit; D Okitoi; J M Sternberg
Journal:  Trans R Soc Trop Med Hyg       Date:  1999 Mar-Apr       Impact factor: 2.184

Review 2.  Analysis of macrophage activation in African trypanosomiasis.

Authors:  D M Paulnock; S P Coller
Journal:  J Leukoc Biol       Date:  2001-05       Impact factor: 4.962

Review 3.  Immunobiology of African trypanosomiasis.

Authors:  J M Sternberg
Journal:  Chem Immunol       Date:  1998

4.  The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors.

Authors:  S Magez; B Stijlemans; M Radwanska; E Pays; M A Ferguson; P De Baetselier
Journal:  J Immunol       Date:  1998-02-15       Impact factor: 5.422

5.  The endogenous balance of soluble tumor necrosis factor receptors and tumor necrosis factor modulates cachexia and mortality in mice acutely infected with Trypanosoma cruzi.

Authors:  C Truyens; F Torrico; R Lucas; P De Baetselier; W A Buurman; Y Carlier
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.441

6.  Effect of melarsoprol treatment on circulating IL-10 and TNF-alpha levels in human African trypanosomiasis.

Authors:  S G Rhind; B H Sabiston; P N Shek; A Buguet; G Muanga; A Stanghellini; M Dumas; M W Radomski
Journal:  Clin Immunol Immunopathol       Date:  1997-05

7.  Relative contribution of interferon-gamma and interleukin-10 to resistance to murine African trypanosomosis.

Authors:  B Namangala; W Noël; P De Baetselier; L Brys; A Beschin
Journal:  J Infect Dis       Date:  2001-05-15       Impact factor: 5.226

8.  Nitric oxide and cytokine synthesis in human African trypanosomiasis.

Authors:  L MacLean; M Odiit; J M Sternberg
Journal:  J Infect Dis       Date:  2001-09-28       Impact factor: 5.226

9.  In vitro simulation of immunosuppression caused by Trypanosoma brucei: active involvement of gamma interferon and tumor necrosis factor in the pathway of suppression.

Authors:  A Darji; A Beschin; M Sileghem; H Heremans; L Brys; P De Baetselier
Journal:  Infect Immun       Date:  1996-06       Impact factor: 3.441

10.  Inducible nitric oxide synthase and nitrotyrosine in the central nervous system of mice chronically infected with Trypanosoma brucei brucei.

Authors:  M Keita; P Vincendeau; A Buguet; R Cespuglio; J M Vallat; M Dumas; B Bouteille
Journal:  Exp Parasitol       Date:  2000-05       Impact factor: 2.011
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  6 in total

1.  Serial cytokine levels in patients with severe sepsis.

Authors:  Huang-Pin Wu; Chian-Kuang Chen; Kong Chung; Jo-Chi Tseng; Chung-Ching Hua; Yu-Chih Liu; Duen-Yau Chuang; Chung-Han Yang
Journal:  Inflamm Res       Date:  2009-03-05       Impact factor: 4.575

Review 2.  Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections.

Authors:  B Bucheton; A MacLeod; V Jamonneau
Journal:  Parasite Immunol       Date:  2011-08       Impact factor: 2.280

3.  The miRNA and mRNA Signatures of Peripheral Blood Cells in Humans Infected with Trypanosoma brucei gambiense.

Authors:  Smiths Lueong; Smiths Leong; Gustave Simo; Mamadou Camara; Vincent Jamonneau; Jacques Kabore; Hamidou Ilboudo; Bruno Bucheton; Jörg D Hoheisel; Christine Clayton
Journal:  PLoS One       Date:  2013-06-27       Impact factor: 3.240

4.  Plasma cytokines quantification among Trypanosoma brucei rhodesiense sleeping sickness cases and controls in Rumphi, Malawi.

Authors:  Kelita Kamoto; Arthur Chiwaya; Peter Nambala; Pricilla Chammudzi; Edward Senga; John Chisi; Enock Matovu; Janelisa Musaya
Journal:  Malawi Med J       Date:  2021-12       Impact factor: 0.875

5.  Trypanosoma brucei rhodesiense transmitted by a single tsetse fly bite in vervet monkeys as a model of human African trypanosomiasis.

Authors:  John K Thuita; John M Kagira; David Mwangangi; Enock Matovu; C M R Turner; Daniel Masiga
Journal:  PLoS Negl Trop Dis       Date:  2008-05-14

Review 6.  The role of cytokines in the pathogenesis and staging of Trypanosoma brucei rhodesiense sleeping sickness.

Authors:  Charles D Kato; Enock Matovu; Claire M Mugasa; Ann Nanteza; Vincent P Alibu
Journal:  Allergy Asthma Clin Immunol       Date:  2016-01-22       Impact factor: 3.406
  6 in total

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