Literature DB >> 15094300

Molecular basis for the chloride channel activity of cystic fibrosis transmembrane conductance regulator and the consequences of disease-causing mutations.

Jackie F Kidd1, Ilana Kogan, Christine E Bear.   

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Year:  2004        PMID: 15094300     DOI: 10.1016/S0070-2153(04)60007-X

Source DB:  PubMed          Journal:  Curr Top Dev Biol        ISSN: 0070-2153            Impact factor:   4.897


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  11 in total

1.  Direct and indirect effects of mutations at the outer mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore.

Authors:  Jing-Jun Zhou; Mohammad Fatehi; Paul Linsdell
Journal:  J Membr Biol       Date:  2007-08-03       Impact factor: 1.843

2.  A synthetic, chloride-selective channel that alters chloride transport in epithelial cells.

Authors:  Robert Pajewski; Raquel Garcia-Medina; Steven L Brody; W Matthew Leevy; Paul H Schlesinger; George W Gokel
Journal:  Chem Commun (Camb)       Date:  2005-11-22       Impact factor: 6.222

3.  Divergent CFTR orthologs respond differently to the channel inhibitors CFTRinh-172, glibenclamide, and GlyH-101.

Authors:  Maximilian Stahl; Klaus Stahl; Marie B Brubacher; John N Forrest
Journal:  Am J Physiol Cell Physiol       Date:  2011-09-21       Impact factor: 4.249

4.  Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function.

Authors:  Man-Song Li; Elizabeth A Cowley; Paul Linsdell
Journal:  Br J Pharmacol       Date:  2012-11       Impact factor: 8.739

5.  The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1-NBD2 heterodimer.

Authors:  Fiona L L Stratford; Mohabir Ramjeesingh; Joanne C Cheung; Ling-Jun Huan; Christine E Bear
Journal:  Biochem J       Date:  2007-01-15       Impact factor: 3.857

6.  Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant.

Authors:  Feng Qian; Yassine El Hiani; Paul Linsdell
Journal:  Pflugers Arch       Date:  2011-07-28       Impact factor: 3.657

7.  ATP hydrolysis-dependent asymmetry of the conformation of CFTR channel pore.

Authors:  Oleg V Krasilnikov; Ravshan Z Sabirov; Yasunobu Okada
Journal:  J Physiol Sci       Date:  2011-04-03       Impact factor: 2.781

8.  Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore.

Authors:  Jing-Jun Zhou; Man-Song Li; Jiansong Qi; Paul Linsdell
Journal:  J Gen Physiol       Date:  2010-02-08       Impact factor: 4.086

9.  Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines.

Authors:  Mohammad Fatehi; Paul Linsdell
Journal:  J Membr Biol       Date:  2009-04-19       Impact factor: 1.843

10.  Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore.

Authors:  Jing-Jun Zhou; Mohammad Fatehi; Paul Linsdell
Journal:  Pflugers Arch       Date:  2008-05-01       Impact factor: 3.657

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