Literature DB >> 15083353

Kyphoplasty for treatment of osteoporotic vertebral fractures: a prospective non-randomized study.

Ulrich Berlemann1, Torsten Franz, Rene Orler, Paul F Heini.   

Abstract

BACKGROUND: Minimally invasive augmentation techniques of vertebral bodies have been advocated to treat osteoporotic vertebral body compression fractures (VBCFs). Kyphoplasty is designed to address both fracture-related pain as well as kyphotic deformity usually associated with fracture. Previous studies have indicated the potential of this technique for reduction of vertebral body height, but there has been little investigation into whether this has a lasting effect. The current study reports on our experience and the one-year results in 27 kyphoplasty procedures (24 patients) for osteoporotic VBCFs.
RESULTS: All but one patient experienced pain relief following the procedure (on VAS 1-10)--with a lasting effect over the follow-up period in 25 cases. An average vertebral kyphosis reduction of 47.7% was achieved with no loss of reduction after one year. The potential for reduction was statistically related to the pre-operative amount of kyphosis, the level treated, and the age of the fracture, but not to the age of the patient. During follow-up, one fracture adjacent to a treated level was observed. Pain relief was not related to the amount of reduction.
CONCLUSION: Kyphoplasty is an effective treatment of VBCFs in terms of pain relief and durable reduction of deformity. Whether spinal realignment results in an improved long-term clinical outcome remains to be investigated.

Entities:  

Mesh:

Year:  2004        PMID: 15083353      PMCID: PMC3476603          DOI: 10.1007/s00586-004-0691-7

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  24 in total

1.  Vertebroplasty: an opportunity to do something really good for patients.

Authors:  T A Einhorn
Journal:  Spine (Phila Pa 1976)       Date:  2000-05-01       Impact factor: 3.468

Review 2.  Osteoporosis.

Authors:  E Truumees
Journal:  Spine (Phila Pa 1976)       Date:  2001-04-15       Impact factor: 3.468

Review 3.  Treatment of painful osteoporotic vertebral fractures with percutaneous vertebroplasty or kyphoplasty.

Authors:  N B Watts; S T Harris; H K Genant
Journal:  Osteoporos Int       Date:  2001       Impact factor: 4.507

4.  New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures.

Authors:  S R Garfin; H A Yuan; M A Reiley
Journal:  Spine (Phila Pa 1976)       Date:  2001-07-15       Impact factor: 3.468

5.  Initial outcome and efficacy of "kyphoplasty" in the treatment of painful osteoporotic vertebral compression fractures.

Authors:  I H Lieberman; S Dudeney; M K Reinhardt; G Bell
Journal:  Spine (Phila Pa 1976)       Date:  2001-07-15       Impact factor: 3.468

6.  Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A prospective study for the treatment of osteoporotic compression fractures.

Authors:  P F Heini; B Wälchli; U Berlemann
Journal:  Eur Spine J       Date:  2000-10       Impact factor: 3.134

7.  Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty.

Authors:  F Grados; C Depriester; G Cayrolle; N Hardy; H Deramond; P Fardellone
Journal:  Rheumatology (Oxford)       Date:  2000-12       Impact factor: 7.580

8.  Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study.

Authors:  B Cortet; A Cotten; N Boutry; R M Flipo; B Duquesnoy; P Chastanet; B Delcambre
Journal:  J Rheumatol       Date:  1999-10       Impact factor: 4.666

9.  Percutaneous vertebroplasty for pain relief and spinal stabilization.

Authors:  J D Barr; M S Barr; T J Lemley; R M McCann
Journal:  Spine (Phila Pa 1976)       Date:  2000-04-15       Impact factor: 3.468

10.  Adjacent vertebral failure after vertebroplasty. A biomechanical investigation.

Authors:  U Berlemann; S J Ferguson; L P Nolte; P F Heini
Journal:  J Bone Joint Surg Br       Date:  2002-07
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  50 in total

1.  Percutaneous balloon kyphoplasty with the patient under intravenous analgesia and sedation: a feasibility study.

Authors:  M Mohr; D Pillich; M Kirsch; J U Mueller; S Fleck; N Hosten; S Langner
Journal:  AJNR Am J Neuroradiol       Date:  2011-01-27       Impact factor: 3.825

2.  Reviewer's comment regarding MS-no: 03/057 entitled: "Kyphoplasty for treatment of osteoporotic vertebral fractures: a prospective non-randomized study" by U. Berlemann et al.

Authors:  Jean-Charles Le Huec
Journal:  Eur Spine J       Date:  2004-05-04       Impact factor: 3.134

Review 3.  [Vertebroplasty: an update: value of percutaneous cement augmentation after randomized, placebo-controlled trials].

Authors:  P F Heini
Journal:  Orthopade       Date:  2010-07       Impact factor: 1.087

4.  Lavage prior to vertebral augmentation reduces the risk for cement leakage.

Authors:  Sven Hoppe; Tarek Elfiky; Marius Johann Baptist Keel; Emin Aghayev; Timo Michael Ecker; Lorin Michael Benneker
Journal:  Eur Spine J       Date:  2015-08-15       Impact factor: 3.134

Review 5.  The Michel Benoist and Robert Mulholland yearly European Spine Journal Review. A survey of the "surgical and research" articles in the European Spine Journal, 2004.

Authors:  Robert C Mulholland
Journal:  Eur Spine J       Date:  2005-01-28       Impact factor: 3.134

Review 6.  Efficacy and safety of balloon kyphoplasty in the treatment of vertebral compression fractures: a systematic review.

Authors:  Carmen Bouza; Teresa López; Angeles Magro; Lourdes Navalpotro; José María Amate
Journal:  Eur Spine J       Date:  2006-01-21       Impact factor: 3.134

7.  Lordoplasty: report on early results with a new technique for the treatment of vertebral compression fractures to restore the lordosis.

Authors:  Rene Orler; Lars H Frauchiger; Uta Lange; Paul F Heini
Journal:  Eur Spine J       Date:  2006-05-25       Impact factor: 3.134

8.  Comparative study of balloon kyphoplasty with unilateral versus bilateral approach in osteoporotic vertebral compression fractures.

Authors:  Hyung Jin Chung; Kook Jin Chung; Hoi Soo Yoon; In Hyup Kwon
Journal:  Int Orthop       Date:  2007-09-03       Impact factor: 3.075

9.  [Operative treatment of traumatic fractures of the thorax and lumbar spine. Part II: surgical treatment and radiological findings].

Authors:  M Reinhold; C Knop; R Beisse; L Audigé; F Kandziora; A Pizanis; R Pranzl; E Gercek; M Schultheiss; A Weckbach; V Bühren; M Blauth
Journal:  Unfallchirurg       Date:  2009-02       Impact factor: 1.000

10.  Reduction of pain and fracture incidence after kyphoplasty: 1-year outcomes of a prospective controlled trial of patients with primary osteoporosis.

Authors:  Ingo A Grafe; Katharina Da Fonseca; Jochen Hillmeier; Peter-Jürgen Meeder; Martin Libicher; Gerd Nöldge; Hubert Bardenheuer; Walter Pyerin; Linus Basler; Christel Weiss; Rod S Taylor; Peter Nawroth; Christian Kasperk
Journal:  Osteoporos Int       Date:  2005-08-03       Impact factor: 4.507

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