Literature DB >> 15082471

Chemokines in joint disease: the key to inflammation?

J J Haringman1, J Ludikhuize, P P Tak.   

Abstract

Targeting chemokines and/or chemokine receptors appears to be an intriguing new approach to treating chronic inflammatory disorders like rheumatoid arthritis, inflammatory bowel diseases, multiple sclerosis, and transplant rejections. The involvement of chemokines and chemokine receptors in inflammatory joint diseases, the in vitro and in vivo characteristics of the chemokine family in inflammatory joint disease, and initial clinical data on chemokine blockade in patients with rheumatoid arthritis suggest that targeting the chemokine and chemokine receptor family might provide a new, promising antirheumatic strategy.

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Year:  2004        PMID： 15082471      PMCID： PMC1754785          DOI： 10.1136/ard.2004.020529

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  119 in total

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  44 in total

1.  Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model.

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Journal:  Arthritis Rheum       Date:  2010-07

2.  Resistin induces expression of proinflammatory cytokines and chemokines in human articular chondrocytes via transcription and messenger RNA stabilization.

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Journal:  Arthritis Rheum       Date:  2010-07

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Journal:  Curr Rheumatol Rep       Date:  2005-10       Impact factor: 4.592

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Authors:  David J Hunter
Journal:  Curr Rheumatol Rep       Date:  2008-01       Impact factor: 4.592

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Authors:  Ahreum Baek; MinGi Kim; Sung Hoon Kim; Sung-Rae Cho; Hyun Jung Kim
Journal:  Inflammation       Date:  2018-03       Impact factor: 4.092

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Journal:  Inflamm Res       Date:  2015-07-20       Impact factor: 4.575

8.  Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis.

Authors:  J J Haringman; T J M Smeets; P Reinders-Blankert; P P Tak
Journal:  Ann Rheum Dis       Date:  2005-08-17       Impact factor: 19.103

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Authors:  L J Sandell; X Xing; C Franz; S Davies; L-W Chang; D Patra
Journal:  Osteoarthritis Cartilage       Date:  2008-06-18       Impact factor: 6.576
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