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Literature DB >> 16174489

Chemokines: their role in rheumatoid arthritis.

Abstract

Chemokines are small proteins that can act on cells that express matching receptors. They are best known for their role in migration of cells, especially immune cells. Chemokine/chemokine-receptor pairs are often functionally categorized into three groups: inflammatory, homeostatic, and angiogenic/angiostatic, although functions sometimes overlap. Interfering with the interaction between chemokines and their receptors is currently under investigation as a therapeutic strategy in rheumatoid arthritis.

Entities: Disease

Mesh：

Substances：

Year: 2005 PMID： 16174489 DOI： 10.1007/s11926-005-0026-7

Source DB: PubMed Journal: Curr Rheumatol Rep ISSN： 1523-3774 Impact factor: 4.592

48 in total

Review 1. Is early rheumatoid arthritis the same disease process as late rheumatoid arthritis?

Authors: P P Tak
Journal: Best Pract Res Clin Rheumatol Date: 2001-03 Impact factor: 4.098

2. Genetic variation in CCR5 does not predict clinical outcome in inflammatory arthritis.

Authors: Sally John; Simon Smith; Jonathan F Morrison; Deborah Symmons; Jane Worthington; Alan Silman; Anne Barton
Journal: Arthritis Rheum Date: 2003-12

3. Synovial tissue macrophage as a source of the chemotactic cytokine IL-8.

Authors: A E Koch; S L Kunkel; J C Burrows; H L Evanoff; G K Haines; R M Pope; R M Strieter
Journal: J Immunol Date: 1991-10-01 Impact factor: 5.422

4. AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.

Authors: P Matthys; S Hatse; K Vermeire; A Wuyts; G Bridger; G W Henson; E De Clercq; A Billiau; D Schols
Journal: J Immunol Date: 2001-10-15 Impact factor: 5.422

Review 5. Specificity of leukocyte-endothelial interactions and diapedesis: physiologic and therapeutic implications of an active decision process.

Authors: E C Butcher
Journal: Res Immunol Date: 1993 Nov-Dec

6. CCR5 (chemokine receptor-5) DNA-polymorphism influences the severity of rheumatoid arthritis.

Authors: I Zapico; E Coto; A Rodríguez; C Alvarez; J C Torre; V Alvarez
Journal: Genes Immun Date: 2000 Impact factor: 2.676

7. Tumor angiogenesis induced by granulocyte chemotactic protein-2 as a countercurrent principle.

Authors: E Van Coillie; I Van Aelst; A Wuyts; R Vercauteren; R Devos; C De Wolf-Peeters; J Van Damme; G Opdenakker
Journal: Am J Pathol Date: 2001-10 Impact factor: 4.307

8. CXCL13 neutralization reduces the severity of collagen-induced arthritis.

Authors: Biao Zheng; Zeynep Ozen; Xuejun Zhang; Swanthri De Silva; Ekaterina Marinova; Linjie Guo; Daniel Wansley; David P Huston; Michael R West; Shuhua Han
Journal: Arthritis Rheum Date: 2005-02

9. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis.

Authors: Jonathan C W Edwards; Leszek Szczepanski; Jacek Szechinski; Anna Filipowicz-Sosnowska; Paul Emery; David R Close; Randall M Stevens; Tim Shaw
Journal: N Engl J Med Date: 2004-06-17 Impact factor: 91.245

10. The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8).

Authors: M C Kraan; D D Patel; J J Haringman; M D Smith; H Weedon; M J Ahern; F C Breedveld; P P Tak
Journal: Arthritis Res Date: 2000-11-09

11 in total

1. Inflammatory synovial fluid microenvironment drives primary human chondrocytes to actively take part in inflammatory joint diseases.

Authors: Eric Röhner; Georg Matziolis; Carsten Perka; Bernd Füchtmeier; Timo Gaber; Gerd-Rüdiger Burmester; Frank Buttgereit; Paula Hoff
Journal: Immunol Res Date: 2012-06 Impact factor: 2.829

2. Synovial angiostatic non-ELR CXC chemokines in inflammatory arthritides: does CXCL4 designate chronicity of synovitis?

Authors: Hakan Erdem; Salih Pay; Ugur Musabak; Ismail Simsek; Ayhan Dinc; Aysel Pekel; Ali Sengul
Journal: Rheumatol Int Date: 2007-01-31 Impact factor: 2.631

3. Monocytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation.

Authors: Caroline Schmutz; Alison Cartwright; Helen Williams; Oliver Haworth; John H H Williams; Andrew Filer; Mike Salmon; Christopher D Buckley; Jim Middleton
Journal: Arthritis Res Ther Date: 2010-08-25 Impact factor: 5.156

10. Identification of diagnostic genes and vital microRNAs involved in rheumatoid arthritis: based on data mining and experimental verification.

Authors: Conglin Ren; Mingshuang Li; Yang Zheng; Fengqing Wu; Weibin Du; Renfu Quan
Journal: PeerJ Date: 2021-05-14 Impact factor: 2.984