BACKGROUND: The indications and results of intraoperative radiofrequency ablation (RFA) of liver metastases (LMs) are not well defined in the literature and have never been compared with those of hepatectomy. The aim of the study was to appreciate the local recurrence rate of RFA in comparison with anatomic and wedge resection. METHODS: Eighty-eight patients with technically unresectable LMs were treated with curative intent. The LMs were treated by anatomic resection (40 patients, 213 LMs) when large, by wedge resection (64 patients, 99 LMs) when peripheral and small, and by RFA (88 patients, 227 LMs) when central and small. The median follow-up was 27.6 months (range, 15-74 months), and a total of 539 LMs were treated (median of 5 per patient). RESULTS: The local recurrence rates were 5.7% for the 227 RFAs, 7.1% for the 99 wedge resections, and 12.5% for the 40 anatomic resections (P =.216). Local recurrence rates after RFA were correlated with LMs larger than 30 mm (P <.001) and with LMs in direct contact with large vessels (P <.001). CONCLUSIONS: RFA is as efficient and safe as wedge or anatomic resections in terms of local control.
BACKGROUND: The indications and results of intraoperative radiofrequency ablation (RFA) of liver metastases (LMs) are not well defined in the literature and have never been compared with those of hepatectomy. The aim of the study was to appreciate the local recurrence rate of RFA in comparison with anatomic and wedge resection. METHODS: Eighty-eight patients with technically unresectable LMs were treated with curative intent. The LMs were treated by anatomic resection (40 patients, 213 LMs) when large, by wedge resection (64 patients, 99 LMs) when peripheral and small, and by RFA (88 patients, 227 LMs) when central and small. The median follow-up was 27.6 months (range, 15-74 months), and a total of 539 LMs were treated (median of 5 per patient). RESULTS: The local recurrence rates were 5.7% for the 227 RFAs, 7.1% for the 99 wedge resections, and 12.5% for the 40 anatomic resections (P =.216). Local recurrence rates after RFA were correlated with LMs larger than 30 mm (P <.001) and with LMs in direct contact with large vessels (P <.001). CONCLUSIONS: RFA is as efficient and safe as wedge or anatomic resections in terms of local control.
Authors: Gianpiero Gravante; John Overton; Roberto Sorge; Neil Bhardwaj; Matthew S Metcalfe; David M Lloyd; Ashley R Dennison Journal: J Gastrointest Surg Date: 2011-02 Impact factor: 3.452
Authors: Lars Frich; Per Kristian Hol; Sumit Roy; Tom Mala; Bjørn Edwin; Ole Petter F Clausen; Ivar P Gladhaug Journal: Eur Radiol Date: 2006-03-16 Impact factor: 5.315
Authors: Stefan Stättner; Florian Primavesi; Vincent S Yip; Robert P Jones; Dietmar Öfner; Hassan Z Malik; Stephen W Fenwick; Graeme J Poston Journal: Surg Today Date: 2014-03-16 Impact factor: 2.549
Authors: Waleed Shady; Elena N Petre; Kinh Gian Do; Mithat Gonen; Hooman Yarmohammadi; Karen T Brown; Nancy E Kemeny; Michael D'Angelica; Peter T Kingham; Stephen B Solomon; Constantinos T Sofocleous Journal: J Vasc Interv Radiol Date: 2017-12-06 Impact factor: 3.464
Authors: Robert P Jones; Declan Dunne; Paul Sutton; Hassan Z Malik; Stephen W Fenwick; Monica Terlizzo; Elizabeth O'Grady; Claus Koelblinger; Stefan Stättner; Stefan Stremitzer; Thomas Gruenberger; Graeme J Poston Journal: HPB (Oxford) Date: 2012-10-16 Impact factor: 3.647