Literature DB >> 15071303

Reovirus type 2 isolated from cerebrospinal fluid.

Laura Hermann1, Joanne Embree, Paul Hazelton, Barbara Wells, R T Kevin Coombs.   

Abstract

An 8-week-old female infant presented with a history of active varicella complicated by Escherichia coli sepsis, oral thrush, hypoalbuminemia, intermittent fevers, diarrhea and feeding intolerance. Rhesus monkey kidney cells inoculated with cerebrospinal fluid revealed reovirus-like particles by electron microscopy. Virus neutralization and RNA-gel electrophoresis studies identified the isolated pathogen as reovirus serotype 2. This report represents one of only a few to isolate reovirus from the central nervous system in humans.

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Year:  2004        PMID： 15071303     DOI： 10.1097/00006454-200404000-00026

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  19 in total

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