| Literature DB >> 15070315 |
Bruce H Lipshutz1, Jeff M Servesko, Tue B Petersen, Patrick P Papa, Andrew A Lover.
Abstract
The reagent combination of catalytic amounts of copper hydride ligated by a nonracemic SEGPHOS ligand leads in situ to an extremely reactive species capable of effecting asymmetric hydrosilylations of conjugated cyclic enones in very high ees. An unprecedented substrate-to-ligand ratio as high as 275 000:1 for this transformation has been documented. [reaction: see text]Entities:
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Year: 2004 PMID： 15070315 DOI： 10.1021/ol0400185
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005