Literature DB >> 15065741

More than the epidemiology of Alzheimer's disease: contributions of the Canadian Study of Health and Aging.

Joan Lindsay1, Elizabeth Sykes, Ian McDowell, René Verreault, Danielle Laurin.   

Abstract

OBJECTIVE: To highlight contributions to knowledge made by the Canadian Study of Health and Aging (CSHA).
METHOD: The CSHA began in 1991, with follow-ups in 1996 and 2001. It was national in scope, with 18 study centres and a coordinating centre. It included 10 263 participants; of these, 9008 were in the community, and 1255 were in institutions. In each phase, community participants were screened for cognitive impairment, and where appropriate, cognitive status was determined by a detailed clinical examination. Data on possible risk factors for dementia were collected at baseline. Data on caring for people with dementia were collected in each phase.
RESULTS: The prevalence of dementia was established at 8% of those aged 65 years and over; incidence (new cases each year) was about 2%. Cognitive impairment not dementia (CIND) was more than twice as common as dementia. Factors affecting the risk of institutionalization, mortality, and the health of caregivers were examined. The costs of dementia were conservatively estimated at dollar 3.9 billion in 1991. Risk factors for Alzheimer's disease (AD) and vascular dementia are presented; it is noteworthy that physical activity appeared to protect against all forms of cognitive decline, particularly for women. Clinical contributions include the development of norms for several neuropsychological tests. Other topics include the health of those with CIND, predicting dementia, medication use, frailty and healthy aging, and urinary incontinence.
CONCLUSION: The CSHA has contributed substantially to knowledge of the epidemiology of dementia, including AD, and to many other topics relevant to seniors' health.

Entities:  

Mesh:

Year:  2004        PMID: 15065741     DOI: 10.1177/070674370404900202

Source DB:  PubMed          Journal:  Can J Psychiatry        ISSN: 0706-7437            Impact factor:   4.356


  13 in total

1.  Status Report--Retracing the history of the early development of national chronic disease surveillance in Canada and the major role of the Laboratory Centre for Disease Control (LCDC) from 1972 to 2000.

Authors:  B C K Choi; D T Wigle; H Johansen; J Losos; M E Fair; E Napke; L J Anderson; J W Davies; K White; A B Miller; F C K Li; S Stachenko; J Lindsay; L A Gaudette; C Nair; I Levy; H Morrison; J Silins; F Bouchard; L Tonmyr; P J Villeneuve; L McRae; K C Johnson; R S Lane; A Probert
Journal:  Health Promot Chronic Dis Prev Can       Date:  2015-04       Impact factor: 3.240

2.  Validation and diagnostic accuracy of predictive curves for age-associated longitudinal cognitive decline in older adults.

Authors:  Patrick J Bernier; Christian Gourdeau; Pierre-Hugues Carmichael; Jean-Pierre Beauchemin; René Verreault; Rémi W Bouchard; Edeltraut Kröger; Robert Laforce
Journal:  CMAJ       Date:  2017-12-04       Impact factor: 8.262

3.  Vitamin D status, cognitive decline and incident dementia: the Canadian Study of Health and Aging.

Authors:  Caroline S Duchaine; Denis Talbot; Mohamed Nafti; Yves Giguère; Sylvie Dodin; André Tourigny; Pierre-Hugues Carmichael; Danielle Laurin
Journal:  Can J Public Health       Date:  2020-02-03

4.  Empirical likelihood-based confidence intervals for length-biased data.

Authors:  J Ning; J Qin; M Asgharian; Y Shen
Journal:  Stat Med       Date:  2012-10-01       Impact factor: 2.373

Review 5.  Impact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease.

Authors:  Simonetta Camandola; Natalie Plick; Mark P Mattson
Journal:  Neurochem Res       Date:  2018-02-08       Impact factor: 3.996

6.  Semiparametric Accelerated Failure Time Model for Length-biased Data with Application to Dementia Study.

Authors:  Jing Ning; Jing Qin; Yu Shen
Journal:  Stat Sin       Date:  2014-01-01       Impact factor: 1.261

7.  Challenges in managing the diet of older adults with early-stage Alzheimer dementia: a caregiver perspective.

Authors:  P Silva; M-J Kergoat; B Shatenstein
Journal:  J Nutr Health Aging       Date:  2013-02       Impact factor: 4.075

Review 8.  Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations.

Authors:  Sam T Creavin; Susanna Wisniewski; Anna H Noel-Storr; Clare M Trevelyan; Thomas Hampton; Dane Rayment; Victoria M Thom; Kirsty J E Nash; Hosam Elhamoui; Rowena Milligan; Anish S Patel; Demitra V Tsivos; Tracey Wing; Emma Phillips; Sophie M Kellman; Hannah L Shackleton; Georgina F Singleton; Bethany E Neale; Martha E Watton; Sarah Cullum
Journal:  Cochrane Database Syst Rev       Date:  2016-01-13

9.  Selecting process quality indicators for the integrated care of vulnerable older adults affected by cognitive impairment or dementia.

Authors:  Edeltraut Kröger; André Tourigny; Diane Morin; Lise Côté; Marie-Jeanne Kergoat; Paule Lebel; Line Robichaud; Shirley Imbeault; Solange Proulx; Zohra Benounissa
Journal:  BMC Health Serv Res       Date:  2007-11-29       Impact factor: 2.655

10.  Mild cognitive impairment: Profile of a cohort from a private sector memory clinic.

Authors:  Srikanth Srinivasan
Journal:  Ann Indian Acad Neurol       Date:  2014-07       Impact factor: 1.383

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