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Literature DB >> 1505860

Biological effects of the antibiotic brefeldin A (decumbin, cyanein, ascotoxin, synergisidin): a retrospective.

Abstract

Brefeldin A has been recently characterized to act as an inhibitor of intracellular protein export with profound effects on the structure and function of the Golgi apparatus in animal cells. Manifold activities of the antibiotic (under different names) published in the 1960's and 1970's are reviewed: effects on fungal growth and morphogenesis, inhibition of mitosis in plant cells, cytotoxicity, cancerostatic, antiviral and antinematodal activity and peculiar effects on DNA, RNA and protein synthesis in microbial and animal cells.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1992 PMID： 1505860 DOI： 10.1007/bf02814572

Source DB: PubMed Journal: Folia Microbiol (Praha) ISSN： 0015-5632 Impact factor: 2.099

48 in total

1. Intracellular accumulation and oligosaccharide processing of alkaline phosphatase under disassembly of the Golgi complex caused by brefeldin A.

Authors: N Takami; K Oda; T Fujiwara; Y Ikehara
Journal: Eur J Biochem Date: 1990-12-27

2. Use of brefeldin A to define sites of glycosphingolipid synthesis: GA2/GM2/GD2 synthase is trans to the brefeldin A block.

Authors: W W Young; M S Lutz; S E Mills; S Lechler-Osborn
Journal: Proc Natl Acad Sci U S A Date: 1990-09 Impact factor: 11.205

3. The action mechanism of brefeldin A. I. Growth recovery of Candida albicans by lipids from the action of brefeldin A.

Authors: T Hayashi; A Takatsuki; G Tamura
Journal: J Antibiot (Tokyo) Date: 1974-01 Impact factor: 2.649

4. [Action of cyaneine in vitro on pathogenic fungi].

Authors: V Betina; E Drouhet; G Segretain
Journal: Ann Inst Pasteur (Paris) Date: 1965-12

5. Antimicrobial properties of fungal macrolide antibiotics.

Authors: V Betina; D Miceková
Journal: Z Allg Mikrobiol Date: 1972

6. Differential effects of brefeldin A on sialylation of N- and O-linked oligosaccharides in low density lipoprotein receptor and epidermal growth factor receptor.

Authors: S Shite; T Seguchi; H Mizoguchi; M Ono; M Kuwano
Journal: J Biol Chem Date: 1990-10-15 Impact factor: 5.157

7. Morphogenic effects of ramihyphin A in filamentous fungi.

Authors: H Baráthová; V Betina; Z Baráth; P Nemec
Journal: Folia Microbiol (Praha) Date: 1975 Impact factor: 2.099

8. Effects of cyanein and ramihyphin A on the dimorphism of Paracoccidioides brasiliensis.

Authors: G San-Blas; F J Yegres
Journal: Folia Microbiol (Praha) Date: 1978 Impact factor: 2.099

9. Glycosylation of the epidermal growth factor receptor and its relationship to membrane transport and ligand binding.

Authors: S Gamou; N Shimizu
Journal: J Biochem Date: 1988-09 Impact factor: 3.387

10. MHC class II-restricted presentation of native protein antigen by B cells is inhibitable by cycloheximide and brefeldin A.

Authors: Y St-Pierre; T H Watts
Journal: J Immunol Date: 1990-08-01 Impact factor: 5.422

15 in total

Review 1. Natural products from plant-associated microorganisms: distribution, structural diversity, bioactivity, and implications of their occurrence.

Authors: A A Leslie Gunatilaka
Journal: J Nat Prod Date: 2006-03 Impact factor: 4.050

2. G.A.T.T. (A General Agreement on Traffic and Transport) and Brefeldin A in Plant Cells.

Authors: B. Satiat-Jeunemaitre; C. Hawes
Journal: Plant Cell Date: 1994-04 Impact factor: 11.277

3. Direct evidence of intracrine angiotensin II signaling in neurons.

Authors: Elena Deliu; G Cristina Brailoiu; Satoru Eguchi; Nicholas E Hoffman; Joseph E Rabinowitz; Douglas G Tilley; Muniswamy Madesh; Walter J Koch; Eugen Brailoiu
Journal: Am J Physiol Cell Physiol Date: 2014-01-08 Impact factor: 4.249

4. An Insight into the Secondary Metabolism of Muscodor yucatanensis: Small-Molecule Epigenetic Modifiers Induce Expression of Secondary Metabolism-Related Genes and Production of New Metabolites in the Endophyte.

Authors: Masroor Qadri; Yedukondalu Nalli; Shreyans K Jain; Asha Chaubey; Asif Ali; Gary A Strobel; Ram A Vishwakarma; Syed Riyaz-Ul-Hassan
Journal: Microb Ecol Date: 2016-12-06 Impact factor: 4.552

5. Intracellular angiotensin II activates rat myometrium.

Authors: Elena Deliu; Andrei A Tica; Dana Motoc; G Cristina Brailoiu; Eugen Brailoiu
Journal: Am J Physiol Cell Physiol Date: 2011-05-25 Impact factor: 4.249

6. Structural correlates of antifungal and cytotoxic activity of brefeldin A: the importance of a rigid planar lactone ring.

Authors: M J Crabbe; V Betina
Journal: Folia Microbiol (Praha) Date: 1994 Impact factor: 2.099

7. Production of brefeldin-A.

Authors: T G McCloud; M P Burns; F D Majadly; G M Muschik; D A Miller; K K Poole; J M Roach; J T Ross; W B Lebherz
Journal: J Ind Microbiol Date: 1995-07

8. Anticancer and antibacterial secondary metabolites from the endophytic fungus Penicillium sp. CAM64 against multi-drug resistant Gram-negative bacteria.

Authors: Jean-Bosco Jouda; Jean-de-Dieu Tamokou; Céline Djama Mbazoa; Prodipta Sarkar; Prasanta Kumar Bag; Jean Wandji
Journal: Afr Health Sci Date: 2016-09 Impact factor: 0.927

9. Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

Authors: J Houbraken; S Kocsubé; C M Visagie; N Yilmaz; X-C Wang; M Meijer; B Kraak; V Hubka; K Bensch; R A Samson; J C Frisvad
Journal: Stud Mycol Date: 2020-06-27 Impact factor: 16.097

10. Intracellular endothelin type B receptor-driven Ca2+ signal elicits nitric oxide production in endothelial cells.

Authors: Elena Deliu; G Cristina Brailoiu; Karthik Mallilankaraman; Hong Wang; Muniswamy Madesh; Ashiwel S Undieh; Walter J Koch; Eugen Brailoiu
Journal: J Biol Chem Date: 2012-10-19 Impact factor: 5.157