Literature DB >> 15054568

Differential production of two antibiotics of Streptomyces coelicolor A3(2), actinorhodin and undecylprodigiosin, upon salt stress conditions.

Beatrica Sevcikova1, Jan Kormanec.   

Abstract

Production of two pigmented antibiotics, actinorhodin and undecylprodigiosin, is differentially affected in Streptomyces coelicolor A3(2) at high salt concentration, with actinorhodin being inhibited and undecylprodigiosin activated. Analysis of expression of two genes coding for pathway-specific transcriptional regulators of actinorhodin and undecylprodigiosin synthesis, actII-ORF4 and redD, revealed that their expression is similarly differentially affected. Thus, the effect of high salt concentration on actinorhodin and undecylprodigiosin production is mediated at the transcriptional level by the differential expression of genes encoding corresponding pathway-specific transcriptional regulators.

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Year:  2004        PMID： 15054568     DOI： 10.1007/s00203-004-0669-1

Source DB:  PubMed          Journal:  Arch Microbiol        ISSN： 0302-8933            Impact factor:   2.552


  9 in total

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Authors:  Cody R Goodwin; Brett C Covington; Dagmara K Derewacz; C Ruth McNees; John P Wikswo; John A McLean; Brian O Bachmann
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2.  Effects of carbon ion beam-induced mutagenesis for the screening of RED production-deficient mutants of Streptomyces coelicolor JCM4020.

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3.  Functional expression of SCO7832 stimulates tautomycetin production via pathway-specific regulatory gene overexpression in Streptomyces sp. CK4412.

Authors:  Shin-Hae Park; Si-Sun Choi; Yoon Jung Kim; Yong Keun Chang; David H Sherman; Eung-Soo Kim
Journal:  J Ind Microbiol Biotechnol       Date:  2009-05-01       Impact factor: 3.346

4.  Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor.

Authors:  Ya-Wen Lu; Adrianna K San Roman; Amy M Gehring
Journal:  J Bacteriol       Date:  2008-08-08       Impact factor: 3.490

5.  Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2).

Authors:  Davide D'Alia; Daniela Eggle; Kay Nieselt; Wei-Shou Hu; Rainer Breitling; Eriko Takano
Journal:  Microb Biotechnol       Date:  2010-12-08       Impact factor: 5.813

6.  Acidic pH shock induces the expressions of a wide range of stress-response genes.

Authors:  Yoon Jung Kim; Myung Hee Moon; Jae Yang Song; Colin P Smith; Soon-Kwang Hong; Yong Keun Chang
Journal:  BMC Genomics       Date:  2008-12-16       Impact factor: 3.969

7.  Mycelium differentiation and development of Streptomyces coelicolor in lab-scale bioreactors: programmed cell death, differentiation, and lysis are closely linked to undecylprodigiosin and actinorhodin production.

Authors:  Beatriz Rioseras; María Teresa López-García; Paula Yagüe; Jesús Sánchez; Angel Manteca
Journal:  Bioresour Technol       Date:  2013-10-30       Impact factor: 9.642

8.  Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2).

Authors:  Wei Lian; Karthik P Jayapal; Salim Charaniya; Sarika Mehra; Frank Glod; Yun-Seung Kyung; David H Sherman; Wei-Shou Hu
Journal:  BMC Genomics       Date:  2008-01-29       Impact factor: 3.969

9.  Production of prodigiosin using tannery fleshing and evaluating its pharmacological effects.

Authors:  C Sumathi; D MohanaPriya; S Swarnalatha; M G Dinesh; G Sekaran
Journal:  ScientificWorldJournal       Date:  2014-01-23
  9 in total

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