Literature DB >> 15047923

Surgical management of spinal metastases.

Paul Klimo1, Meic H Schmidt.   

Abstract

Metastatic spread to the spinal column is a growing problem in patients with cancer. It can cause a number of sequelae including pain, instability, and neurologic deficit. If left untreated, progressive myelopathy results in the loss of motor, sensory, and autonomic functions. Except in rare circumstances, treatment is palliative. Traditionally, conventional fractionated external beam radiotherapy has been the treatment of choice. "Surgery" for metastatic spinal disease was, and generally continues to be, equated with laminectomy by many physicians. However, there has been a remarkable evolution in surgical techniques over the last 20 years. Today, the goal of surgery is to achieve circumferential decompression of the neural elements while reconstructing and immediately stabilizing the spinal column. This has been made possible by the use of different surgical approaches and the exploitation of a burgeoning array of internal fixation devices. More recently, minimally invasive surgical techniques, such as endoscopy, kyphoplasty/vertebroplasty, and stereotactic radiosurgery, have been added to the surgeon's armamentarium. As the number of treatment options for metastatic spinal disease grows, it has become clear that effective implementation of treatment can only be achieved by a multidisciplinary approach. This will provide the surest means of maximizing the quality of the remainder of the patient's life.

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Year:  2004        PMID: 15047923     DOI: 10.1634/theoncologist.9-2-188

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  87 in total

1.  Intra-operative vertebroplasty combined with posterior cord decompression. A report of twelve cases.

Authors:  Luca Allegretti; Nicola Mavilio; Pietro Fiaschi; Roberto Bragazzi; Mattia Pacetti; Lara Castelletti; Laura Saitta; Lucio Castellan
Journal:  Interv Neuroradiol       Date:  2014-10-17       Impact factor: 1.610

2.  Percutaneous vertebroplasty in vertebral metastases from breast cancer: interest in terms of pain relief and quality of life.

Authors:  Héctor Manuel Barragán-Campos; Anne-Laurence Le Faou; Michèle Rose; Alain Livartowski; Marianne Doz; Pascal Astagneau; Evelyne Cormier; Jacques Chiras
Journal:  Interv Neuroradiol       Date:  2014-10-17       Impact factor: 1.610

3.  Percutaneous balloon kyphoplasty with the patient under intravenous analgesia and sedation: a feasibility study.

Authors:  M Mohr; D Pillich; M Kirsch; J U Mueller; S Fleck; N Hosten; S Langner
Journal:  AJNR Am J Neuroradiol       Date:  2011-01-27       Impact factor: 3.825

Review 4.  Cervical spine metastases: techniques for anterior reconstruction and stabilization.

Authors:  Christina M Sayama; Meic H Schmidt; Erica F Bisson
Journal:  Neurosurg Rev       Date:  2012-04-29       Impact factor: 3.042

Review 5.  Management of metastatic sacral tumours.

Authors:  Nasir A Quraishi; Kyriakos E Giannoulis; Kimberley L Edwards; Bronek M Boszczyk
Journal:  Eur Spine J       Date:  2012-06-23       Impact factor: 3.134

6.  Pattern of Tumour Spread of Common Primary Tumours as Seen on Magnetic Resonance Imaging.

Authors:  David Laszlo Tarnoki; Adam Domonkos Tarnoki; Susanne Ohlmann-Knafo; Dirk Pickuth
Journal:  Pathol Oncol Res       Date:  2015-08-30       Impact factor: 3.201

7.  A meta-analysis of surgery versus conventional radiotherapy for the treatment of metastatic spinal epidural disease.

Authors:  Paul Klimo; Clinton J Thompson; John R W Kestle; Meic H Schmidt
Journal:  Neuro Oncol       Date:  2005-01       Impact factor: 12.300

Review 8.  [Compression syndromes].

Authors:  J Wierecky; C Bokemeyer
Journal:  Internist (Berl)       Date:  2005-01       Impact factor: 0.743

9.  Which MR imaging sequences are necessary in determining the need for radiation therapy for cord compression? A prospective study.

Authors:  A J Johnson; J Ying; T El Gammal; R D Timmerman; R Y Kim; B Littenberg
Journal:  AJNR Am J Neuroradiol       Date:  2007-01       Impact factor: 3.825

Review 10.  Metastatic spinal lesions: state-of-the-art treatment options and future trends.

Authors:  B A Georgy
Journal:  AJNR Am J Neuroradiol       Date:  2008-06-19       Impact factor: 3.825

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