Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Molecular defects in insulin secretion in type-2 diabetes.

Literature DB >> 15041789

Molecular defects in insulin secretion in type-2 diabetes.

Frances M Ashcroft¹, Patrik Rorsman.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2004 PMID： 15041789 DOI： 10.1023/B:REMD.0000021435.87776.a7

Source DB: PubMed Journal: Rev Endocr Metab Disord ISSN： 1389-9155 Impact factor: 6.514

× No keyword cloud information.

70 in total

Review 1. Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.

Authors: S S Fajans; G I Bell; K S Polonsky
Journal: N Engl J Med Date: 2001-09-27 Impact factor: 91.245

2. E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.

Authors: L Love-Gregory; J Wasson; J Lin; G Skolnick; B Suarez; M A Permutt
Journal: Diabetologia Date: 2003-01 Impact factor: 10.122

3. Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53).

Authors: A L Gloyn; Y Hashim; S J Ashcroft; R Ashfield; S Wiltshire; R C Turner
Journal: Diabet Med Date: 2001-03 Impact factor: 4.359

4. Perchlorate stimulates insulin secretion by shifting the gating of L-type Ca2+ currents in mouse pancreatic B-cells towards negative potentials.

Authors: G Larsson-Nyrén; J Sehlin; P Rorsman; E Renström
Journal: Pflugers Arch Date: 2001-02 Impact factor: 3.657

Review 5. Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes.

Authors: C B Wollheim
Journal: Diabetologia Date: 2000-03 Impact factor: 10.122

6. Targeted overactivity of beta cell K(ATP) channels induces profound neonatal diabetes.

Authors: J C Koster; B A Marshall; N Ensor; J A Corbett; C G Nichols
Journal: Cell Date: 2000-03-17 Impact factor: 41.582

Review 7. Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets.

Authors: P E MacDonald; M B Wheeler
Journal: Diabetologia Date: 2003-06-27 Impact factor: 10.122

Review 8. Glucokinase mutations, insulin secretion, and diabetes mellitus.

Authors: G I Bell; S J Pilkis; I T Weber; K S Polonsky
Journal: Annu Rev Physiol Date: 1996 Impact factor: 19.318

9. Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese.

Authors: Yukio Horikawa; Naohisa Oda; Li Yu; Shigeo Imamura; Kentaro Fujiwara; Masaki Makino; Yutaka Seino; Mitsuyasu Itoh; Jun Takeda
Journal: J Clin Endocrinol Metab Date: 2003-01 Impact factor: 5.958

10. Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification.

Authors: S Barg; P Huang; L Eliasson; D J Nelson; S Obermüller; P Rorsman; F Thévenod; E Renström
Journal: J Cell Sci Date: 2001-06 Impact factor: 5.285

14 in total

1. Glucose increases activity and Ca2+ in insulin-producing cells of adult Drosophila.

Authors: Orsolya Kréneisz; Xinnian Chen; Yih-Woei C Fridell; Daniel K Mulkey
Journal: Neuroreport Date: 2010-12-08 Impact factor: 1.837

Review 2. Glucose-sensing mechanisms in pancreatic beta-cells.

Authors: Patrick E MacDonald; Jamie W Joseph; Patrik Rorsman
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2005-12-29 Impact factor: 6.237

3. Delayed onset of hyperglycaemia in a mouse model with impaired glucagon secretion demonstrates that dysregulated glucagon secretion promotes hyperglycaemia and type 2 diabetes.

Authors: N Gustavsson; T Seah; Y Lao; G K Radda; T C Südhof; W Han
Journal: Diabetologia Date: 2010-10-27 Impact factor: 10.122

Review 4. Interplay between Rab27a effectors in pancreatic β-cells.

Authors: Mami Yamaoka; Toshimasa Ishizaki; Toshihide Kimura
Journal: World J Diabetes Date: 2015-04-15

5. Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan.

Authors: Yih-Woei C Fridell; Melissa Hoh; Orsolya Kréneisz; Suzanne Hosier; Chengyi Chang; Dane Scantling; Daniel K Mulkey; Stephen L Helfand
Journal: Aging (Albany NY) Date: 2009-07-21 Impact factor: 5.682

6. Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice.

Authors: Natalia Gustavsson; Ye Lao; Anton Maximov; Jen-Chieh Chuang; Elena Kostromina; Joyce J Repa; Cai Li; George K Radda; Thomas C Südhof; Weiping Han
Journal: Proc Natl Acad Sci U S A Date: 2008-02-28 Impact factor: 11.205

7. An exploratory study of the association between KCNB1 rs1051295 and type 2 diabetes and its related traits in Chinese Han population.

Authors: Yu-Xiang Zhang; Yan Liu; Jing Dong; You-Xin Wang; Jing Wang; Guo-Qing Zhuang; Shu-Jing Han; Qing-Qing Guo; Yan-Xia Luo; Jie Zhang; Xiao-Xia Peng; Ling Zhang; Yu-Xiang Yan; Xing-Hua Yang; Hong Wang; Xu Han; Guang-Xu Liu; You-Hou Kang; You-Qin Liu; Sheng-Feng Weng; Hong Zhang; Xiao-Qiang Zhang; Ke-Bao Jia; Li Wang; Lei Zhao; Zhong-Xin Xiao; Shu-Hua Zhang; Hui-Hui Wu; Qing-Xuan Lai; Na Qi; Wei Wang; Herbert Gaisano; Fen Liu; Yan He
Journal: PLoS One Date: 2013-02-19 Impact factor: 3.240