Literature DB >> 15041786

Insulin signaling defects in type 2 diabetes.

Ying Leng1, Håkan K R Karlsson, Juleen R Zierath.   

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Year:  2004        PMID： 15041786     DOI： 10.1023/B:REMD.0000021432.84588.f6

Source DB:  PubMed          Journal:  Rev Endocr Metab Disord        ISSN： 1389-9155            Impact factor:   6.514


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  46 in total

1.  Defective insulin receptor tyrosine kinase in human skeletal muscle in obesity and type 2 (non-insulin-dependent) diabetes mellitus.

Authors:  P Arner; T Pollare; H Lithell; J N Livingston
Journal:  Diabetologia       Date:  1987-06       Impact factor: 10.122

2.  Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1.

Authors:  J A Le Good; W H Ziegler; D B Parekh; D R Alessi; P Cohen; P J Parker
Journal:  Science       Date:  1998-09-25       Impact factor: 47.728

3.  Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes.

Authors:  J F Caro; M K Sinha; S M Raju; O Ittoop; W J Pories; E G Flickinger; D Meelheim; G L Dohm
Journal:  J Clin Invest       Date:  1987-05       Impact factor: 14.808

4.  A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain.

Authors:  Susan Kane; Hiroyuki Sano; Simon C H Liu; John M Asara; William S Lane; Charles C Garner; Gustav E Lienhard
Journal:  J Biol Chem       Date:  2002-05-06       Impact factor: 5.157

5.  Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance.

Authors:  Joseph T Brozinick; Brian R Roberts; G Lynis Dohm
Journal:  Diabetes       Date:  2003-04       Impact factor: 9.461

6.  Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients.

Authors:  A Krook; M Björnholm; D Galuska; X J Jiang; R Fahlman; M G Myers; H Wallberg-Henriksson; J R Zierath
Journal:  Diabetes       Date:  2000-02       Impact factor: 9.461

7.  Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus.

Authors:  A Vaag; J E Henriksen; H Beck-Nielsen
Journal:  J Clin Invest       Date:  1992-03       Impact factor: 14.808

Review 8.  Peroxisome proliferator-activated receptors (PPARS): regulators of gene expression in heart and skeletal muscle.

Authors:  A J Gilde; M Van Bilsen
Journal:  Acta Physiol Scand       Date:  2003-08

9.  Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.

Authors:  Yoshinori Miyazaki; Helen He; Lawrence J Mandarino; Ralph A DeFronzo
Journal:  Diabetes       Date:  2003-08       Impact factor: 9.461

Review 10.  Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling.

Authors:  P R Shepherd; D J Withers; K Siddle
Journal:  Biochem J       Date:  1998-08-01       Impact factor: 3.857
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  20 in total

1.  Regulation of carbohydrate metabolism by indole-3-carbinol and its metabolite 3,3'-diindolylmethane in high-fat diet-induced C57BL/6J mice.

Authors:  Jayakumar Poornima; Sankaran Mirunalini
Journal:  Mol Cell Biochem       Date:  2013-09-27       Impact factor: 3.396

Review 2.  Genetic variants associated with insulin signaling and glucose homeostasis in the pathogenesis of insulin resistance in polycystic ovary syndrome: a systematic review.

Authors:  Bhaskar Venkata Kameswara Subrahmanya Lakkakula; Maheswari Thangavelu; Usha Rani Godla
Journal:  J Assist Reprod Genet       Date:  2013-06-22       Impact factor: 3.412

3.  Gastric Sleeve Surgery Alleviates Obesity-Associated Insulin Resistance and Suppresses Endoplasmic Reticulum Stress in Adipose Tissue of db/db Mice.

Authors:  Ming Sun; Wenyan Zhao; Shuqiang Li; Chunfei Li; Yong Feng; Donghua Geng
Journal:  Obes Surg       Date:  2019-10       Impact factor: 4.129

4.  Effect of a novel non-thiazolidinedione peroxisome proliferator-activated receptor alpha/gamma agonist on glucose uptake.

Authors:  X Hu; Y Feng; X Liu; X-F Zhao; J-H Yu; Y-S Yang; M Sydow-Bäckman; J Hörling; J R Zierath; Y Leng
Journal:  Diabetologia       Date:  2007-03-01       Impact factor: 10.122

5.  Postreceptoral adipocyte insulin resistance induced by nelfinavir is caused by insensitivity of PKB/Akt to phosphatidylinositol-3,4,5-trisphosphate.

Authors:  Ilana Kachko; Adva Maissel; Livnat Mazor; Ronit Ben-Romano; Robert T Watson; June C Hou; Jeffrey E Pessin; Nava Bashan; Assaf Rudich
Journal:  Endocrinology       Date:  2009-01-29       Impact factor: 4.736

6.  Irs1 serine 307 promotes insulin sensitivity in mice.

Authors:  Kyle D Copps; Nancy J Hancer; Lynn Opare-Ado; Wei Qiu; Cari Walsh; Morris F White
Journal:  Cell Metab       Date:  2010-01       Impact factor: 27.287

7.  Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2.

Authors:  A Suwa; T Yamamoto; A Sawada; K Minoura; N Hosogai; A Tahara; T Kurama; T Shimokawa; I Aramori
Journal:  Br J Pharmacol       Date:  2009-08-19       Impact factor: 8.739

Review 8.  Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle.

Authors:  Michael G Clark
Journal:  Am J Physiol Endocrinol Metab       Date:  2008-07-08       Impact factor: 4.310

Review 9.  The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities.

Authors:  Ira D Goldfine; Betty A Maddux; Jack F Youngren; Gerald Reaven; Domenico Accili; Vincenzo Trischitta; Riccardo Vigneri; Lucia Frittitta
Journal:  Endocr Rev       Date:  2008-01-16       Impact factor: 19.871

10.  Increased skeletal muscle tumor necrosis factor-alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum.

Authors:  Jacob E Friedman; John P Kirwan; Ming Jing; Larraine Presley; Patrick M Catalano
Journal:  Diabetes       Date:  2007-12-14       Impact factor: 9.461
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