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Literature DB >> 15041075

Discrimination between normal and malignant human gastric tissues by Fourier transform infrared spectroscopy.

Naoko Fujioka¹, Yuji Morimoto, Tsunenori Arai, Makoto Kikuchi.

Abstract

The aim of this study was to determine whether malignant and normal human gastric tissues can be distinguished by Fourier transform infrared (FTIR) spectroscopy. Compared with normal tissue, malignant tissues showed significant increases in infrared (IR) absorption in 10 bands lying in a region of 925-1660 cm(-1). Using the 10 IR absorption bands as markers, discriminant analysis was carried out for tissue discrimination. As a result, 22 out of the 23 gastric cancer samples and 9 out of the 12 gastric normal samples were correctly segregated, yielding 88.6% accuracy. The present results suggest that FTIR spectroscopy is a useful tool for screening gastric cancer.

Entities: Disease Species

Mesh：

Year: 2004 PMID： 15041075 DOI： 10.1016/j.cdp.2003.11.004

Source DB: PubMed Journal: Cancer Detect Prev ISSN： 0361-090X

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Cited

21 in total

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Discrimination between normal and malignant human gastric tissues by Fourier transform infrared spectroscopy.

1. Diagnosis of basal cell carcinoma by infrared spectroscopy of whole blood samples applying soft independent modeling class analogy.

2. Use of Fourier-transform infrared spectroscopy to rapidly diagnose gastric endoscopic biopsies.

3. Species identification of bloodstains by ATR-FTIR spectroscopy: the effects of bloodstain age and the deposition environment.

4. Detection of Cancer Metastasis Using a Novel Macroscopic Hyperspectral Method.

5. Biogenic synthesis of silver nanoparticle by using secondary metabolites from Pseudomonas aeruginosa DM1 and its anti-algal effect on Chlorella vulgaris and Chlorella pyrenoidosa.

6. Use of an endoscope-compatible probe to detect colonic dysplasia with Fourier transform infrared spectroscopy.

7. Gastric Cancer Regional Detection System.

8. Evaluation of FTIR spectroscopy as a diagnostic tool for lung cancer using sputum.

9. Detection of colonic inflammation with Fourier transform infrared spectroscopy using a flexible silver halide fiber.

10. Identification of colitis and cancer in colon biopsies by Fourier Transform Infrared spectroscopy and chemometrics.