Literature DB >> 15038036

Synthetic strategy toward skeletal diversity via solid-supported, otherwise unstable reactive intermediates.

Steven J Taylor1, Alexander M Taylor, Stuart L Schreiber.   

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Year:  2004        PMID： 15038036     DOI： 10.1002/anie.200353466

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  11 in total

1.  Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules.

Authors:  Warren R J D Galloway; Albert Isidro-Llobet; David R Spring
Journal:  Nat Commun       Date:  2010-09-21       Impact factor: 14.919

2.  Solid-phase synthesis and chemical space analysis of a 190-membered alkaloid/terpenoid-like library.

Authors:  Gustavo Moura-Letts; Christine M Diblasi; Renato A Bauer; Derek S Tan
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-30       Impact factor: 11.205

3.  Diversity through a branched reaction pathway: generation of multicyclic scaffolds and identification of antimigratory agents.

Authors:  Zhiming Wang; Sabrina Castellano; Sape S Kinderman; Christian E Argueta; Anwar B Beshir; Gabriel Fenteany; Ohyun Kwon
Journal:  Chemistry       Date:  2010-11-09       Impact factor: 5.236

4.  The tert-butylsulfinamide lynchpin in transition-metal-mediated multiscaffold library synthesis.

Authors:  Renato A Bauer; Christine M DiBlasi; Derek S Tan
Journal:  Org Lett       Date:  2010-05-07       Impact factor: 6.005

5.  Skeletal and Appendage Diversity as Design Elements in the Synthesis of a Discovery Library of Nonaromatic Polycyclic 5-Iminooxazolidin-2-ones, Hydantoins, and Acylureas.

Authors:  S Werner; D M Turner; P G Chambers; K M Brummond
Journal:  Tetrahedron       Date:  2008-07-14       Impact factor: 2.457

6.  A unified synthetic approach to polyketides having both skeletal and stereochemical diversity.

Authors:  Shiying Shang; Hayato Iwadare; Daniel E Macks; Lisa M Ambrosini; Derek S Tan
Journal:  Org Lett       Date:  2007-04-17       Impact factor: 6.005

7.  Small-Molecule Library Synthesis on Silicon-Functionalized SynPhase Lanterns.

Authors:  Jeremy R Duvall; Anita Vrcic; Lisa A Marcaurelle
Journal:  Curr Protoc Chem Biol       Date:  2010-07-01

8.  Synthesis of isoquinuclidines from highly substituted dihydropyridines via the Diels-Alder reaction.

Authors:  Rhia M Martin; Robert G Bergman; Jonathan A Ellman
Journal:  Org Lett       Date:  2013-01-15       Impact factor: 6.005

9.  Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.

Authors:  Jason T Lowe; Maurice D Lee; Lakshmi B Akella; Emeline Davoine; Etienne J Donckele; Landon Durak; Jeremy R Duvall; Baudouin Gerard; Edward B Holson; Adrien Joliton; Sarathy Kesavan; Berenice C Lemercier; Haibo Liu; Jean-Charles Marié; Carol A Mulrooney; Giovanni Muncipinto; Morgan Welzel-O'Shea; Laura M Panko; Ann Rowley; Byung-Chul Suh; Meryl Thomas; Florence F Wagner; Jingqiang Wei; Michael A Foley; Lisa A Marcaurelle
Journal:  J Org Chem       Date:  2012-08-10       Impact factor: 4.354

10.  Stereoselective synthesis of isoquinuclidines through an aza-[4 + 2] cycloaddition of chiral cyclic 2-amidodienes.

Authors:  Li-Chao Fang; Richard P Hsung
Journal:  Org Lett       Date:  2014-03-12       Impact factor: 6.005
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