Literature DB >> 15036032

Antigenic variation in African trypanosomes: monitoring progress.

Richard McCulloch1.   

Abstract

Antigenic variation is central to the success of African trypanosomes and other eukaryotic, bacterial and viral pathogens. Our understanding of the control and execution of this immune evasion strategy in trypanosomes is incomplete, despite the molecular basis of antigenic variation being first described over 20 years ago. Recent research progress in this field is highlighted here and some of the unresolved questions raised.

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Year:  2004        PMID： 15036032     DOI： 10.1016/j.pt.2003.12.004

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  21 in total

1.  Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms.

Authors:  Eleanor M Barnwell; Frederick J van Deursen; Laura Jeacock; Katherine A Smith; Rick M Maizels; Alvaro Acosta-Serrano; Keith Matthews
Journal:  J Cell Sci       Date:  2010-09-07       Impact factor: 5.285

Review 2.  Reconstructing immune phylogeny: new perspectives.

Authors:  Gary W Litman; John P Cannon; Larry J Dishaw
Journal:  Nat Rev Immunol       Date:  2005-11       Impact factor: 53.106

3.  In vitro generation of human high-density-lipoprotein-resistant Trypanosoma brucei brucei.

Authors:  Sara D Faulkner; Monika W Oli; Rudo Kieft; Laura Cotlin; Justin Widener; April Shiflett; Michael J Cipriano; Sarah E Pacocha; Shanda R Birkeland; Stephen L Hajduk; Andrew G McArthur
Journal:  Eukaryot Cell       Date:  2006-08

Review 4.  New insights into the molecular mechanisms of mitosis and cytokinesis in trypanosomes.

Authors:  Qing Zhou; Huiqing Hu; Ziyin Li
Journal:  Int Rev Cell Mol Biol       Date:  2014       Impact factor: 6.813

Review 5.  The developmental cell biology of Trypanosoma brucei.

Authors:  Keith R Matthews
Journal:  J Cell Sci       Date:  2005-01-15       Impact factor: 5.285

6.  Pharmacokinetics, Trypanosoma brucei gambiense efficacy, and time of drug action of DB829, a preclinical candidate for treatment of second-stage human African trypanosomiasis.

Authors:  Tanja Wenzler; Sihyung Yang; Olivier Braissant; David W Boykin; Reto Brun; Michael Zhuo Wang
Journal:  Antimicrob Agents Chemother       Date:  2013-08-19       Impact factor: 5.191

7.  Characterization of major surface protease homologues of Trypanosoma congolense.

Authors:  Veronica Marcoux; Guojian Wei; Henry Tabel; Harold J Bull
Journal:  J Biomed Biotechnol       Date:  2010-01-20

8.  Immunolocalization and challenge studies using a recombinant Vibrio cholerae ghost expressing Trypanosoma brucei Ca(2+) ATPase (TBCA2) antigen.

Authors:  Kiantra Ramey; Francis O Eko; Winston E Thompson; Henry Armah; Joseph U Igietseme; Jonathan K Stiles
Journal:  Am J Trop Med Hyg       Date:  2009-09       Impact factor: 2.345

Review 9.  Restless gossamers: antibody clearance by hydrodynamic flow forces generated at the surface of motile trypanosome parasites.

Authors:  Samuel D Dean; Keith R Matthews
Journal:  Cell Host Microbe       Date:  2007-11-15       Impact factor: 21.023

10.  Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei.

Authors:  Sarah Kabani; Katelyn Fenn; Alan Ross; Al Ivens; Terry K Smith; Peter Ghazal; Keith Matthews
Journal:  BMC Genomics       Date:  2009-09-11       Impact factor: 3.969
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