Literature DB >> 1503594

Synthesis, spectral studies and biological activities of some N-bridged heterocycles derived from 3-arylaminomethyl-4-amino-5-mercapto-1,2,4-triazoles.

B S Holla1, K V Udupa.   

Abstract

Synthesis of four 3-arylaminomethyl-4-amino-5-mercapto-1,2,4-triazoles starting from substituted anilines is described. These triazoles were employed in the synthesis of some N-bridged heterocycles carrying arylaminomethyl substituents. All the newly synthesized compounds were characterized by analytical, NMR and mass spectral studies. Some of the newly synthesized compounds were screened for their antibacterial and antiviral properties.

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Year:  1992        PMID: 1503594

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  6 in total

1.  Synthesis and Anti-Cancer Activity of New Pyrazolinyl-Indole Derivatives: Pharmacophoric Interactions and Docking Studies for Identifying New EGFR Inhibitors.

Authors:  Habibullah Khalilullah; Deepak K Agarwal; Mohamed J Ahsan; Surender S Jadav; Hamdoon A Mohammed; Masood Alam Khan; Salman A A Mohammed; Riaz Khan
Journal:  Int J Mol Sci       Date:  2022-06-11       Impact factor: 6.208

2.  2-Phenoxy-acetohydrazide.

Authors:  Hoong-Kun Fun; Ching Kheng Quah; Arun M Isloor; Dhanya Sunil; Prakash Shetty
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-12-04

3.  2-(4-Methyl-phen-oxy)acetohydrazide.

Authors:  Hoong-Kun Fun; Ching Kheng Quah; Shridhar Malladi; Vijesh A M; Arun M Isloor
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-12-18

4.  2-(2-Chloro-phen-oxy)acetohydrazide.

Authors:  Hoong-Kun Fun; Ching Kheng Quah; Arun M Isloor; Dhanya Sunil; Prakash Shetty
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-12-04

5.  4-Amino-3-[(4-methoxy-phen-yl)amino-meth-yl]-1H-1,2,4-triazole-5(4H)-thione.

Authors:  Hoong-Kun Fun; Chin Sing Yeap; Shridhar Malladi; Mahesh Padaki; Arun M Isloor
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-08-22

6.  2-(4-Methyl-anilino)acetohydrazide.

Authors:  Hoong-Kun Fun; Chin Sing Yeap; Shridhar Malladi; Mahesh Padaki; Arun M Isloor
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-08-26
  6 in total

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