Literature DB >> 15035737

Treating inflammation: some (needless) difficulties for gaining acceptance of effective natural products and traditional medicines.

D E Butters1, M W Whitehouse.   

Abstract

The quality of so-called 'natural medicines' is extraordinarily variable. Lack of resolute pharmacological assays contributes to this hiatus. More stringent evaluation of anti-inflammatory and anti-pyretic activities in rats can help resolve some of the uncertainties surrounding (a) preparations of some herbal products including so-called 'nature's aspirin' (e.g. willowbark, ginger), cat's claw, celery seed, etc., and (b) some animal lipids (e.g. Lyprinol(R) (NZ Mussel), emu and fish oils). These animal products can be a remarkable resource for supplementing conventional/allopathic therapy for inflammatory disease, e.g. providing lipoxygenase inhibitors. Beyond the verifiable science, the healing professions and the general public still need to examine more carefully criteria for QUALITY(S) in any alternative medicine-to ensure the good (= both reputations and products) are not destroyed by the bad-in essence counteracting Gresham's Law which states: the bad tends to displace the good.

Entities:  

Year:  2003        PMID: 15035737     DOI: 10.1163/156856003321547149

Source DB:  PubMed          Journal:  Inflammopharmacology        ISSN: 0925-4692            Impact factor:   4.473


  18 in total

1.  Effects of a ginger extract on knee pain in patients with osteoarthritis.

Authors:  R D Altman; K C Marcussen
Journal:  Arthritis Rheum       Date:  2001-11

2.  Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans.

Authors:  J I Schwartz; C C Chan; S Mukhopadhyay; K J McBride; T M Jones; S Adcock; C Moritz; J Hedges; K Grasing; D Dobratz; R A Cohen; M H Davidson; K A Bachmann; B J Gertz
Journal:  Clin Pharmacol Ther       Date:  1999-06       Impact factor: 6.875

3.  Green-lipped mussel extract in arthritis.

Authors:  R G Gibson; S L Gibson
Journal:  Lancet       Date:  1981-02-21       Impact factor: 79.321

4.  Gingerols and related analogues inhibit arachidonic acid-induced human platelet serotonin release and aggregation.

Authors:  K L Koo; A J Ammit; V H Tran; C C Duke; B D Roufogalis
Journal:  Thromb Res       Date:  2001-09-01       Impact factor: 3.944

5.  Perna canaliculus in the treatment of rheumatoid arthritis.

Authors:  D E Caughey; R R Grigor; E B Caughey; P Young; P J Gow; A W Stewart
Journal:  Eur J Rheumatol Inflamm       Date:  1983

6.  Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis.

Authors:  T D Warner; F Giuliano; I Vojnovic; A Bukasa; J A Mitchell; J R Vane
Journal:  Proc Natl Acad Sci U S A       Date:  1999-06-22       Impact factor: 11.205

7.  A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis.

Authors:  H Bliddal; A Rosetzsky; P Schlichting; M S Weidner; L A Andersen; H H Ibfelt; K Christensen; O N Jensen; J Barslev
Journal:  Osteoarthritis Cartilage       Date:  2000-01       Impact factor: 6.576

8.  Over the counter (OTC) oral remedies for arthritis and rheumatism: how effective are they?

Authors:  M W Whitehouse; M S Roberts; P M Brooks
Journal:  Inflammopharmacology       Date:  1999       Impact factor: 4.473

9.  Anti-inflammatory activity of emu oils in rats.

Authors:  J M Snowden; M W Whitehouse
Journal:  Inflammopharmacology       Date:  1997       Impact factor: 4.473

10.  Effect of ginger & garlic on DNA content of gastric aspirate.

Authors:  H G Desai; R H Kalro; A P Choksi
Journal:  Indian J Med Res       Date:  1990-04       Impact factor: 2.375

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  2 in total

1.  A toxicological investigation of a celery seed extract having anti-inflammatory activity.

Authors:  M C Powanda; K D Rainsford
Journal:  Inflammopharmacology       Date:  2010-06-22       Impact factor: 4.473

2.  Combination anti-inflammatory therapy: synergism in rats of NSAIDs/corticosteroids with some herbal/animal products.

Authors:  M W Whitehouse; D E Butters
Journal:  Inflammopharmacology       Date:  2003       Impact factor: 4.473

  2 in total

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