Literature DB >> 15032686

Microwave - assisted chemistry in drug discovery.

Farah Mavandadi1, Pelle Lidström.   

Abstract

Microwave assisted organic synthesis (MAOS) is rapidly gaining acceptance as a valuable tool for relieving some of the bottlenecks in the drug discovery process. This article outlines the basic principles behind the technology and summarizes recent trends and areas in drug discovery where microwave technology has made an impact.

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Year:  2004        PMID： 15032686     DOI： 10.2174/1568026043451078

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  6 in total

Review 1.  Controlled microwave heating in modern organic synthesis: highlights from the 2004-2008 literature.

Authors:  C Oliver Kappe; Doris Dallinger
Journal:  Mol Divers       Date:  2009-04-21       Impact factor: 2.943

2.  Preparation of 6-substituted quinoxaline JSP-1 inhibitors by microwave accelerated nucleophilic substitution.

Authors:  Li Zhang; Beiying Qiu; Xin Li; Xin Wang; Jingya Li; Yongliang Zhang; Jian Liu; Jia Li; Jingkang Shen
Journal:  Molecules       Date:  2006-12-21       Impact factor: 4.411

Review 3.  Microwave Irradiation: Alternative Heating Process for the Synthesis of Biologically Applicable Chromones, Quinolones, and Their Precursors.

Authors:  Hélio M T Albuquerque; Diana C G A Pinto; Artur M S Silva
Journal:  Molecules       Date:  2021-10-18       Impact factor: 4.411

4.  Quinazoline derivatives: synthesis and bioactivities.

Authors:  Dan Wang; Feng Gao
Journal:  Chem Cent J       Date:  2013-06-03       Impact factor: 4.215

5.  Rapid synthesis and antiviral activity of (quinazolin-4-ylamino)methyl-phosphonates through microwave irradiation.

Authors:  Hui Luo; Deyu Hu; Jian Wu; Ming He; Linhong Jin; Song Yang; Baoan Song
Journal:  Int J Mol Sci       Date:  2012-06-01       Impact factor: 6.208

6.  Synthesis of gamma-nitro aliphatic methyl esters via Michael additions promoted by microwave irradiation.

Authors:  Jaime Escalante; Francisco D Díaz-Coutiño
Journal:  Molecules       Date:  2009-04-21       Impact factor: 4.411
  6 in total

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