Elizabeth A Yoder1, Kenneth Klann, Kingman P Strohl. 1. Louis Stokes Cleveland DVA Medical Center, Medical Service, Center for Sleep Disorders Research, Case Western Reserve University, Cleveland, Ohio, USA. Beth.Yoder@att.net
Abstract
OBJECTIVES: This study examined the effects of various factors that might influence the fraction of oxygen in inspired air (FiO (2)) in a human and in a model system during nasal positive pressure treatments. DESIGN AND METHODS: A healthy male volunteer and a mannequin head were each outfitted with a nasal continuous positive air pressure mask and pressure source (BiPAP S, Respironics, Murrysville, PA). Oxygen was added through either a side port in the mask or a port near the machine. Flow and FiO (2) were measured while varying inspiratory and expiratory pressures. Measurements were repeated with a leak added to the system and using different sites of oxygen administration. RESULTS: In both the human and in the model system, increasing inspiratory pressure, thereby increasing flow, decreased FiO (2) inside the mask. In the model system, addition of a fixed leak caused an increase in flow and decrease in FiO (2) at any given level of inspiratory and expiratory pressure. CONCLUSION: In patients using nasal positive pressure therapy, variables of pressure, leak around the mask, and the site of oxygen delivery determine the inspired oxygen concentration when giving oxygen supplementation.
OBJECTIVES: This study examined the effects of various factors that might influence the fraction of oxygen in inspired air (FiO (2)) in a human and in a model system during nasal positive pressure treatments. DESIGN AND METHODS: A healthy male volunteer and a mannequin head were each outfitted with a nasal continuous positive air pressure mask and pressure source (BiPAP S, Respironics, Murrysville, PA). Oxygen was added through either a side port in the mask or a port near the machine. Flow and FiO (2) were measured while varying inspiratory and expiratory pressures. Measurements were repeated with a leak added to the system and using different sites of oxygen administration. RESULTS: In both the human and in the model system, increasing inspiratory pressure, thereby increasing flow, decreased FiO (2) inside the mask. In the model system, addition of a fixed leak caused an increase in flow and decrease in FiO (2) at any given level of inspiratory and expiratory pressure. CONCLUSION: In patients using nasal positive pressure therapy, variables of pressure, leak around the mask, and the site of oxygen delivery determine the inspired oxygen concentration when giving oxygen supplementation.
Authors: Ayodeji Adegunsoye; Julie M Neborak; Daisy Zhu; Benjamin Cantrill; Nicole Garcia; Justin M Oldham; Imre Noth; Rekha Vij; Tomasz J Kuzniar; Shashi K Bellam; Mary E Strek; Babak Mokhlesi Journal: Chest Date: 2020-05-22 Impact factor: 9.410
Authors: Richard B Berry; Alejandro Chediak; Lee K Brown; Jonathan Finder; David Gozal; Conrad Iber; Clete A Kushida; Timothy Morgenthaler; James A Rowley; Sally L Davidson-Ward Journal: J Clin Sleep Med Date: 2010-10-15 Impact factor: 4.062
Authors: Clete A Kushida; Alejandro Chediak; Richard B Berry; Lee K Brown; David Gozal; Conrad Iber; Sairam Parthasarathy; Stuart F Quan; James A Rowley Journal: J Clin Sleep Med Date: 2008-04-15 Impact factor: 4.062