Literature DB >> 15018740

A phase I vaccine safety and chemotherapy dose-finding trial of an allogeneic GM-CSF-secreting breast cancer vaccine given in a specifically timed sequence with immunomodulatory doses of cyclophosphamide and doxorubicin.

Leisha A Emens1, Deborah Armstrong, Barbara Biedrzycki, Nancy Davidson, Janice Davis-Sproul, John Fetting, Elizabeth Jaffee, Beth Onners, Steve Piantadosi, Richard T Reilly, Vered Stearns, Irena Tartakovsky, Kala Visvanathan, Antonio Wolff.   

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Year:  2004        PMID: 15018740     DOI: 10.1089/104303404322886165

Source DB:  PubMed          Journal:  Hum Gene Ther        ISSN: 1043-0342            Impact factor:   5.695


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  18 in total

1.  Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine.

Authors:  Shiwen Peng; Sofia Lyford-Pike; Belinda Akpeng; Annie Wu; Chien-Fu Hung; Drew Hannaman; John R Saunders; T-C Wu; Sara I Pai
Journal:  Cancer Immunol Immunother       Date:  2012-08-04       Impact factor: 6.968

Review 2.  Chemotherapy and tumor immunity: an unexpected collaboration.

Authors:  Leisha A Emens
Journal:  Front Biosci       Date:  2008-01-01

3.  Vaccine impedes the development of reflux-induced esophageal cancer in a surgical rat model: efficacy of the vaccine in a Pre-Barrett's esophagus setting.

Authors:  Tomoharu Miyashita; Furhawn A Shah; Guy Marti; Jiaai Wang; Todd Armstrong; Pramod Bonde; Michael K Gibson; Kiyoshi Yoshimura; Elizabeth A Montgomery; Mark D Duncan; Elizabeth M Jaffee; John W Harmon
Journal:  J Gastrointest Surg       Date:  2007-10-24       Impact factor: 3.452

4.  Vaccine impedes the development of reflux-induced esophageal cancer in a surgical rat model: efficacy of the vaccine in a post-Barrett's esophagus setting.

Authors:  Tomoharu Miyashita; Furhawn A Shah; Guy P Marti; Todd D Armstrong; Jiaai Wang; Pramod Bonde; Michael K Gibson; Kiyoshi Yoshimura; Elizabeth A Montgomery; Mark Duncan; Elizabeth M Jaffee; John W Harmon
Journal:  Dig Dis Sci       Date:  2008-03-15       Impact factor: 3.199

5.  Synergy of topical toll-like receptor 7 agonist with radiation and low-dose cyclophosphamide in a mouse model of cutaneous breast cancer.

Authors:  M Zahidunnabi Dewan; Claire Vanpouille-Box; Noriko Kawashima; Sara DiNapoli; James S Babb; Silvia C Formenti; Sylvia Adams; Sandra Demaria
Journal:  Clin Cancer Res       Date:  2012-10-09       Impact factor: 12.531

6.  A bystander cell-based GM-CSF secreting vaccine synergized with a low dose of cyclophosphamide presents therapeutic immune responses against murine hepatocellular carcinoma.

Authors:  Chen Chen; Jiajie Hou; Zhe Lin; Ming Yao; Runqiu Jiang; Youjing Wang; Yun Gao; Qing Shao; Lei Deng; Yun Chen; Beicheng Sun
Journal:  Cell Mol Immunol       Date:  2013-05-20       Impact factor: 11.530

7.  Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model.

Authors:  Satoshi Wada; Kiyoshi Yoshimura; Edward L Hipkiss; Tim J Harris; Hung-Rong Yen; Monica V Goldberg; Joseph F Grosso; Derese Getnet; Angelo M Demarzo; George J Netto; Robert Anders; Drew M Pardoll; Charles G Drake
Journal:  Cancer Res       Date:  2009-05-12       Impact factor: 12.701

Review 8.  Allogeneic tumor cell vaccines: the promise and limitations in clinical trials.

Authors:  Sanjay Srivatsan; Jaina M Patel; Erica N Bozeman; Imade E Imasuen; Sara He; Danielle Daniels; Periasamy Selvaraj
Journal:  Hum Vaccin Immunother       Date:  2013-09-24       Impact factor: 3.452

Review 9.  Cancer immunotherapy: the role regulatory T cells play and what can be done to overcome their inhibitory effects.

Authors:  Ulf Petrausch; Christian H Poehlein; Shawn M Jensen; Chris Twitty; James A Thompson; Ilka Assmann; Sachin Puri; Michael G LaCelle; Tarsem Moudgil; Levi Maston; Kevin Friedman; Sarah Church; Elisa Cardenas; Daniel P Haley; Edwin B Walker; Emmanuel Akporiaye; Andrew D Weinberg; Sidney Rosenheim; Todd S Crocenzi; Hong-Ming Hu; Brendan D Curti; Walter J Urba; Bernard A Fox
Journal:  Curr Mol Med       Date:  2009-08       Impact factor: 2.222

10.  Combining low-dose cyclophosphamide with GM-CSF-secreting prostate cancer immunotherapy enhances antitumor immune effects.

Authors:  Emmanuel S Antonarakis; Michael A Carducci
Journal:  Expert Opin Investig Drugs       Date:  2010-02       Impact factor: 6.206

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