Literature DB >> 15017577

Nitrous oxide analgesia for minor pediatric surgical procedures: an effective alternative to conscious sedation?

Cathy Burnweit1, Jeannette A Diana-Zerpa, Michel H Nahmad, Charles A Lankau, Malvin Weinberger, Leo Malvezzi, Lisa Smith, Tina Shapiro, Kristine Thayer.   

Abstract

BACKGROUND/
PURPOSE: Minor surgical procedures in children, while usually not requiring general anesthesia, need effective control of pain, anxiety, and motion. Certain techniques of conscious sedation may result in loss of protective airway reflexes. Nitrous oxide, however, when inhaled at levels below 50% maintains protective reflexes and does not require fasting or postprocedure monitoring. This study prospectively examines the efficacy of nitrous oxide analgesia in children undergoing outpatient surgical procedures.
METHODS: Over a 2-year period (2000 to 2002), 150 consecutive children were given nitrous oxide analgesia as an alternative to a general anesthetic, sedation, or local anesthetic alone. Nitrous oxide (<50%) was administered by our practice's sedation-certified nurse practitioner without an anesthesiologist present. The children used the Wong-Baker Faces Scale (0-5) to score pain at different intervals (preprocedure, at injection, during procedure, and postprocedure) and event memories were tabulated.
RESULTS: Of 150 children, 5 were uncooperative and could not participate. One hundred forty-five children, ages 1 to 20 years (Mean, 9.83 +/- 4.92 years) successfully underwent procedures (58 cyst/nevus excisions, 49 abscess drainages, 38 other) using nitrous. Two patients were too young to score pain. Pre- and postprocedure pain scores were significantly higher in the abscess group (P <.0001); during the procedures, however, all groups reported pain scores less than 1, with parents citing 100% satisfaction with the technique. Of 128 children receiving local anesthesia, 107 (84%) had no recall of the injection. Complications were limited to 4 patients; 2 experienced nausea, and 2 vomited. All resolved without interrupting the procedure.
CONCLUSIONS: Nitrous oxide analgesia is a cost-effective and efficacious alternative to conscious sedation or general anesthesia for minor pediatric surgical procedures. In the office or outpatient setting, the technique provides for almost pain/anxiety-free surgery, no postoperative monitoring, and a high degree of satisfaction for patients, parents, and staff.

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Year:  2004        PMID: 15017577     DOI: 10.1016/j.jpedsurg.2003.11.037

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  9 in total

1.  Does relative analgesia with nitrous oxide reduce the number of general anaesthetic sessions and dental loss?

Authors:  P Souto; N Robb
Journal:  Br Dent J       Date:  2018-03-23       Impact factor: 1.626

2.  The Association Between Opioid Use and Outcomes in Infants Undergoing Pyloromyotomy.

Authors:  Cory McLaughlin; Anthony I Squillaro; Shadassa Ourshaliman; Ashley Song; Ashwini Lakshmanan; Giovanni Cucchiaro; Matthew Hall; Rita V Burke; Lorraine I Kelley-Quon
Journal:  Clin Ther       Date:  2019-08-10       Impact factor: 3.393

3.  Nitrous oxide procedural sedation in non-fasting pediatric patients undergoing minor surgery: a 12-year experience with 1,058 patients.

Authors:  Raquel Pasarón; Cathy Burnweit; Jeannette Zerpa; Leopoldo Malvezzi; Colin Knight; Tina Shapiro; Carmen Ramos-Irizarry; Evelio Velis
Journal:  Pediatr Surg Int       Date:  2014-11-11       Impact factor: 1.827

4.  Temperament as a Predictor of Nitrous Oxide Inhalation Sedation Success.

Authors:  Travis M Nelson; Thomas M Griffith; Katherine J Lane; Sarat Thikkurissy; JoAnna M Scott
Journal:  Anesth Prog       Date:  2017

5.  Pediatric Procedural Sedation and Analgesia (PROSA) in the Leuven University Hospitals: An Audit on Efficacy and Safety.

Authors:  Lotte Kerkhofs; Karel Allegaert; Jaan Toelen; Koen Vanhonsebrouck
Journal:  Children (Basel)       Date:  2022-05-25

6.  Pediatric procedural sedation and analgesia.

Authors:  James R Meredith; Kelly P O'Keefe; Sagar Galwankar
Journal:  J Emerg Trauma Shock       Date:  2008-07

7.  Sedation with nitrous oxide compared with no sedation during catheterization for urologic imaging in children.

Authors:  Judith L Zier; Kathryn A Kvam; Stephen C Kurachek; Marsha Finkelstein
Journal:  Pediatr Radiol       Date:  2007-05-22

8.  Professional skills and competence for safe and effective procedural sedation in children: recommendations based on a systematic review of the literature.

Authors:  Piet L J M Leroy; Daphne M Schipper; Hans J T A Knape
Journal:  Int J Pediatr       Date:  2010-06-28

Review 9.  Complications caused by nitrous oxide in dental sedation.

Authors:  Seong In Chi
Journal:  J Dent Anesth Pain Med       Date:  2018-04-27
  9 in total

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