Literature DB >> 15015728

Kigamicins, novel antitumor antibiotics. II. Structure determination.

Setsuko Kunimoto1, Tetsuya Someno, Yohko Yamazaki, Jie Lu, Hiroyasu Esumi, Hiroshi Naganawa.   

Abstract

Kigamicin A (1), B (2), C (3), D (4) and E (5) are novel antitumor antibiotics. Their structures were determined by spectroscopic analyses including various NMR measurements. Kigamicins have a unique aglycone of fused octacyclic ring system containing seven of six-membered rings and one oxazolidine. The aglycone links a sugar chain composed of one to four deoxysugars. These sugars were found to be amicetose and oleandrose.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 15015728     DOI: 10.7164/antibiotics.56.1012

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  9 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

2.  Total synthesis and absolute stereochemical assignment of kibdelone C.

Authors:  David L Sloman; Jeffrey W Bacon; John A Porco
Journal:  J Am Chem Soc       Date:  2011-06-15       Impact factor: 15.419

3.  Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives.

Authors:  Janjira Rujirawanich; Soyeon Kim; Ai-Jun Ma; John R Butler; Yizhong Wang; Chao Wang; Michael Rosen; Bruce Posner; Deepak Nijhawan; Joseph M Ready
Journal:  J Am Chem Soc       Date:  2016-08-09       Impact factor: 15.419

Review 4.  Polycyclic xanthone natural products: structure, biological activity and chemical synthesis.

Authors:  Dana K Winter; David L Sloman; John A Porco
Journal:  Nat Prod Rep       Date:  2013-01-21       Impact factor: 13.423

5.  Anticancer potential of metabolic compounds from marine actinomycetes isolated from Lagos Lagoon sediment.

Authors:  Olabisi Flora Davies-Bolorunduro; Isaac Adeyemi Adeleye; Moshood Olushola Akinleye; Peng George Wang
Journal:  J Pharm Anal       Date:  2019-03-14

Review 6.  Isolation, Biosynthesis, and Biological Activity of Polycyclic Xanthones From Actinomycetes.

Authors:  Hui-Qing Yu; Gang Li; Hong-Xiang Lou
Journal:  Front Microbiol       Date:  2022-07-13       Impact factor: 6.064

7.  Olefin cross metathesis based de novo synthesis of a partially protected L-amicetose and a fully protected L-cinerulose derivative.

Authors:  Bernd Schmidt; Sylvia Hauke
Journal:  Beilstein J Org Chem       Date:  2014-05-06       Impact factor: 2.883

8.  Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition.

Authors:  Takefumi Onodera; Isao Momose; Hayamitsu Adachi; Yohko Yamazaki; Ryuichi Sawa; Shun-Ichi Ohba; Manabu Kawada
Journal:  J Biol Chem       Date:  2020-09-25       Impact factor: 5.157

9.  Arixanthomycins A-C: Phylogeny-guided discovery of biologically active eDNA-derived pentangular polyphenols.

Authors:  Hahk-Soo Kang; Sean F Brady
Journal:  ACS Chem Biol       Date:  2014-04-30       Impact factor: 5.100

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.