Literature DB >> 1501228

Sulfonylureas: a new class of cancer chemotherapeutic agents.

F Mohamadi1, M M Spees, G B Grindey.   

Abstract

This study summarizes the antitumor properties of a number of sulofenur thiophene analogs against subcutaneously implanted 6C3HED lymphosarcoma with structural modification of the aryl moiety of the sulfonamide portion of the diarylsulfonylureas. The spectrum of activity of N-(p-chlorophenyl)-N'- [(5-methoxy-2-thienyl)sulfonyl]urea in the HXGC3, VRC5, CX-1, and LX-1 cell lines is also presented.

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Year:  1992        PMID： 1501228     DOI： 10.1021/jm00094a013

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  10 in total

1.  Atypical cytostatic mechanism of N-1-sulfonylcytosine derivatives determined by in vitro screening and computational analysis.

Authors:  Fran Supek; Marijeta Kralj; Marko Marjanović; Lidija Suman; Tomislav Smuc; Irena Krizmanić; Biserka Zinić
Journal:  Invest New Drugs       Date:  2007-09-27       Impact factor: 3.850

2.  Design, synthesis, and biological evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine and its analogs as a novel class of anticancer agents.

Authors:  Wei Chen; Teresa Seefeldt; Alan Young; Xiaoying Zhang; Xiangming Guan
Journal:  Bioorg Med Chem       Date:  2010-11-13       Impact factor: 3.641

3.  In vivo toxicity study of N-1-sulfonylcytosine derivatives and their mechanisms of action in cervical carcinoma cell line.

Authors:  Jelena Kašnar-Šamprec; Ivana Ratkaj; Katarina Mišković; Marina Pavlak; Mirela Baus-Lončar; Sandra Kraljević Pavelić; Ljubica Glavaš-Obrovac; Biserka Žinić
Journal:  Invest New Drugs       Date:  2011-03-22       Impact factor: 3.850

Review 4.  Effects of sulfonylureas on tumor growth: a review of the literature.

Authors:  Giulia Pasello; Loredana Urso; Pierfranco Conte; Adolfo Favaretto
Journal:  Oncologist       Date:  2013-09-16

5.  Synthesis and antitumor evaluation of novel sulfonylcycloureas derived from nitrogen mustard.

Authors:  H Cheloufi; B Belhani; T S Ouk; R Zerrouki; N-E Aouf; M Berredjem
Journal:  Mol Divers       Date:  2015-11-23       Impact factor: 2.943

6.  Synthesis, characterization, antioxidant activity and DNA-binding studies of three rare earth (III) complexes with 1-(4-aminoantipyrine)-3-tosylurea ligand.

Authors:  Pin-xian Xi; Zhi-hong Xu; Xiao-hui Liu; Feng-juan Chen; Zheng-zhi Zeng; Xiao-wen Zhang; Ying Liu
Journal:  J Fluoresc       Date:  2008-06-04       Impact factor: 2.217

7.  A phase I study of sulofenur in refractory pediatric malignant solid tumors.

Authors:  C B Pratt; L C Bowman; N Marina; A Pappo; L Avery; X Luo; W H Meyer
Journal:  Invest New Drugs       Date:  1995       Impact factor: 3.850

8.  Time-dependent density functional theory calculations of the solvatochromism of some azo sulfonamide fluorochromes.

Authors:  Przemysław Krawczyk
Journal:  J Mol Model       Date:  2015-04-16       Impact factor: 1.810

Review 9.  Glutathione S-conjugates as prodrugs to target drug-resistant tumors.

Authors:  Emma E Ramsay; Pierre J Dilda
Journal:  Front Pharmacol       Date:  2014-08-11       Impact factor: 5.810

10.  Experiment stands corrected: accurate prediction of the aqueous pK a values of sulfonamide drugs using equilibrium bond lengths.

Authors:  Beth A Caine; Maddalena Bronzato; Paul L A Popelier
Journal:  Chem Sci       Date:  2019-05-29       Impact factor: 9.825
  10 in total

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