Literature DB >> 15012135

Metallophosphites as umpolung catalysts: the enantioselective cross silyl benzoin reaction.

Xin Linghu1, Justin R Potnick, Jeffrey S Johnson.   

Abstract

Carbonyl polarity reversal (umpolung) has been realized employing metallophosphites as catalysts. As a result, nonenzymatic asymmetric cross silyl benzoin reactions have been achieved, giving optically active silyl ether-protected benzoin adducts. The reaction is general with respect to aryl, alkyl, and heterocyclic substrates with good to excellent yields and good to excellent enantioselectivities.

Entities:  

Year:  2004        PMID： 15012135     DOI： 10.1021/ja0496468

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  21 in total

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2.  Umpolung catalysts: comparative assessments on reactivities.

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6.  Catalytic nucleophilic glyoxylation of aldehydes.

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7.  Lanthanum tricyanide-catalyzed acyl silane-ketone benzoin additions and kinetic resolution of resultant alpha-silyloxyketones.

Authors:  James C Tarr; Jeffrey S Johnson
Journal:  J Org Chem       Date:  2010-05-21       Impact factor: 4.354

8.  Metallophosphite-induced nucleophilic acylation of alpha,beta-unsaturated amides: facilitated catalysis by a diastereoselective retro [1,4] Brook rearrangement.

Authors:  Mary R Nahm; Xin Linghu; Justin R Potnick; Christopher M Yates; Peter S White; Jeffrey S Johnson
Journal:  Angew Chem Int Ed Engl       Date:  2005-04-15       Impact factor: 15.336

9.  Synthesis of Complex Glycolates by Enantioconvergent Addition Reactions.

Authors:  Samuel L Bartlett; Jeffrey S Johnson
Journal:  Acc Chem Res       Date:  2017-08-17       Impact factor: 22.384

10.  Metallophosphite-catalyzed asymmetric acylation of alpha,beta-unsaturated amides.

Authors:  Mary R Nahm; Justin R Potnick; Peter S White; Jeffrey S Johnson
Journal:  J Am Chem Soc       Date:  2006-03-01       Impact factor: 15.419
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