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Literature DB >> 15012117

Dissociation behavior of doubly-charged tryptic peptides: correlation of gas-phase cleavage abundance with ramachandran plots.

Yingying Huang¹, Joseph M Triscari, Ljiljana Pasa-Tolic, Gordon A Anderson, Mary S Lipton, Richard D Smith, Vicki H Wysocki.

Abstract

Analysis of fragmentation patterns from 5654 unique doubly charged tryptic peptides is obtained. Great variability of average relative abundance of bond cleavage is found between different amino acid combinations. There exist similarities as well as differences between b and y ions. Strong enhancement or suppression of cleavage gives insight into possible chemical interactions at reactive conformations formed by preferred phi-psi angles.

Entities: Chemical

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Year: 2004 PMID： 15012117 DOI： 10.1021/ja038041t

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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Cited

22 in total

1. Gas-phase conformation-specific photofragmentation of proline-containing peptide ions.

Authors: Tae-Young Kim; Stephen J Valentine; David E Clemmer; James P Reilly
Journal: J Am Soc Mass Spectrom Date: 2010-04-18 Impact factor: 3.109

2. Statistical characterization of the charge state and residue dependence of low-energy CID peptide dissociation patterns.

Authors: Yingying Huang; Joseph M Triscari; George C Tseng; Ljiljana Pasa-Tolic; Mary S Lipton; Richard D Smith; Vicki H Wysocki
Journal: Anal Chem Date: 2005-09-15 Impact factor: 6.986

3. A data-mining scheme for identifying peptide structural motifs responsible for different MS/MS fragmentation intensity patterns.

Authors: Yingying Huang; George C Tseng; Shinsheng Yuan; Ljiljana Pasa-Tolic; Mary S Lipton; Richard D Smith; Vicki H Wysocki
Journal: J Proteome Res Date: 2007-12-04 Impact factor: 4.466

4. Evaluation of the influence of amino acid composition on the propensity for collision-induced dissociation of model peptides using molecular dynamics simulations.

Authors: William R Cannon; Danny Taasevigen; Douglas J Baxter; Julia Laskin
Journal: J Am Soc Mass Spectrom Date: 2007-06-20 Impact factor: 3.109

10. Effects of single amino acid substitution on the collision-induced dissociation of intact protein ions: Turkey ovomucoid third domain.

Authors: Kelly A Newton; Sharon J Pitteri; Michael Laskowski; Scott A McLuckey
Journal: J Proteome Res Date: 2004 Sep-Oct Impact factor: 4.466

Dissociation behavior of doubly-charged tryptic peptides: correlation of gas-phase cleavage abundance with ramachandran plots.

1. Gas-phase conformation-specific photofragmentation of proline-containing peptide ions.

2. Statistical characterization of the charge state and residue dependence of low-energy CID peptide dissociation patterns.

3. A data-mining scheme for identifying peptide structural motifs responsible for different MS/MS fragmentation intensity patterns.

4. Evaluation of the influence of amino acid composition on the propensity for collision-induced dissociation of model peptides using molecular dynamics simulations.

Review 5. Surface-induced dissociation of small molecules, peptides, and non-covalent protein complexes.

6. Bifurcating fragmentation behavior of gas-phase tryptic peptide dications in collisional activation.

7. Charge states of y ions in the collision-induced dissociation of doubly charged tryptic peptide ions.

8. Combinatorial Labeling Method for Improving Peptide Fragmentation in Mass Spectrometry.

9. Comprehensive mass spectrometric mapping of the hydroxylated amino acid residues of the α1(V) collagen chain.

10. Effects of single amino acid substitution on the collision-induced dissociation of intact protein ions: Turkey ovomucoid third domain.