Literature DB >> 15012073

No-D NMR (no-deuterium proton NMR) spectroscopy: a simple yet powerful method for analyzing reaction and reagent solutions.

Thomas R Hoye1, Brian M Eklov, Troy D Ryba, Mikhail Voloshin, Letitia J Yao.   

Abstract

[reaction: see text] The title technique is a convenient and powerful method for directly monitoring or assaying any reaction mixture or reagent solution. Examples of some common processes (Fischer esterification, lithiation, butyllithium/THF compatibility, olefin metathesis, and a quantification assay), each interrogated in its native solvent, are presented. The spectral data are easy to acquire, and the information content makes a compelling case for routine use of No-D NMR spectroscopy.

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Year:  2004        PMID: 15012073     DOI: 10.1021/ol049979+

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  12 in total

1.  CATALYTIC DYNAMIC RESOLUTION APPLIED TO THE SYNTHESIS OF 2,6-DISUBSTITUTED PIPERIDINES: PREPARATION OF (+)-LUPETIDINE AND (-)-EPIDIHYDROPINIDINE.

Authors:  Timothy K Beng; Robert E Gawley
Journal:  Heterocycles       Date:  2012-01-01       Impact factor: 0.831

2.  Total synthesis of peloruside A through kinetic lactonization and relay ring-closing metathesis cyclization reactions.

Authors:  Thomas R Hoye; Junha Jeon; Lucas C Kopel; Troy D Ryba; Manomi A Tennakoon; Yini Wang
Journal:  Angew Chem Int Ed Engl       Date:  2010-08-16       Impact factor: 15.336

3.  Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions.

Authors:  Bhaumik A Pandya; Sivaraman Dandapani; Jeremy R Duvall; Ann Rowley; Carol A Mulrooney; Troy Ryba; Michael Dombrowski; Marie Harton; Damian W Young; Lisa A Marcaurelle
Journal:  Tetrahedron       Date:  2011-08-26       Impact factor: 2.457

4.  Anomalies in the asymmetric transfer hydrogenation of several polycyclic meso compounds.

Authors:  David R Clay; Matthias C McIntosh
Journal:  Tetrahedron Lett       Date:  2012-01-14       Impact factor: 2.415

5.  Synthesis and reactivity of palladium(II) fluoride complexes containing nitrogen-donor ligands.

Authors:  Nicholas D Ball; Jeff W Kampf; Melanie S Sanford
Journal:  Dalton Trans       Date:  2009-11-26       Impact factor: 4.390

6.  In Situ Catalyst Generation and Benchtop-Compatible Entry Points for TiII/TiIV Redox Catalytic Reactions.

Authors:  Zachary W Davis-Gilbert; Kento Kawakita; Daniel R Blechschmidt; Hayato Tsurugi; Kazushi Mashima; Ian A Tonks
Journal:  Organometallics       Date:  2018-09-06       Impact factor: 3.876

7.  Diethylzinc-Mediated Metalloamination-Alkylation of N, N-Dimethylhydrazinoalkenes. Catalysis of C-Zn Alkylation Using Simple Cu(I) Salts.

Authors:  Ky Mickelsen; Sean Zabawa; Tom Livinghouse
Journal:  Synlett       Date:  2017-10-12       Impact factor: 2.454

8.  Examples Showing the Utility of Doping Experiments in 1H NMR Analysis of Mixtures.

Authors:  Trinadh Kaicharla; Bhavani Shankar Chinta; Thomas R Hoye
Journal:  J Org Chem       Date:  2022-04-20       Impact factor: 4.198

9.  Dynamic kinetic asymmetric transformations of β-stereogenic α-ketoesters by direct aldolization.

Authors:  Michael T Corbett; Jeffrey S Johnson
Journal:  Angew Chem Int Ed Engl       Date:  2013-11-12       Impact factor: 15.336

10.  Alkane desaturation by concerted double hydrogen atom transfer to benzyne.

Authors:  Dawen Niu; Patrick H Willoughby; Brian P Woods; Beeraiah Baire; Thomas R Hoye
Journal:  Nature       Date:  2013-09-26       Impact factor: 49.962

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