BACKGROUND: Waterproofing agents are widely applied to leather and textile garments; they are also used as floor stain protectors by professionals. Acute respiratory injury is described in three cases of young healthy adults following occupational inhalation of a new waterproofing formulation containing an acrylate fluoropolymer. Within 1 or 2 h after exposure they developed a rapidly progressive dyspnoea; two of them had hypoxaemia and flu-like reactions. All patients improved with supportive treatment in a few days. The mechanism of toxicity is still under investigation, but experimental data suggest the role of this new acrylate fluoropolymer. CONCLUSION: Tilers should be warned against spraying floor stain repellents; there is also a need to make consumers aware that the spraying of waterproofing agents in a closed environment and concomitant smoking should be avoided.
BACKGROUND: Waterproofing agents are widely applied to leather and textile garments; they are also used as floor stain protectors by professionals. Acute respiratory injury is described in three cases of young healthy adults following occupational inhalation of a new waterproofing formulation containing an acrylate fluoropolymer. Within 1 or 2 h after exposure they developed a rapidly progressive dyspnoea; two of them had hypoxaemia and flu-like reactions. All patients improved with supportive treatment in a few days. The mechanism of toxicity is still under investigation, but experimental data suggest the role of this new acrylate fluoropolymer. CONCLUSION: Tilers should be warned against spraying floor stain repellents; there is also a need to make consumers aware that the spraying of waterproofing agents in a closed environment and concomitant smoking should be avoided.
Authors: A F Hubbs; V Castranova; J Y Ma; D G Frazer; P D Siegel; B S Ducatman; A Grote; D Schwegler-Berry; V A Robinson; C Van Dyke; M Barger; J Xiang; J Parker Journal: Toxicol Appl Pharmacol Date: 1997-03 Impact factor: 4.219
Authors: Asger W Nørgaard; Søren T Larsen; Maria Hammer; Steen S Poulsen; Keld A Jensen; Gunnar D Nielsen; Peder Wolkoff Journal: Toxicol Sci Date: 2010-03-26 Impact factor: 4.849
Authors: Paul T J Scheepers; Lucie Masen-Poos; Frits G B G J van Rooy; Arné Oerlemans; Eline van Daalen; Robbert Cremers; Hera Lichtenbeld; Bonne Biesma; Jorid B Sørli; Ismo K Koponen; Søren Thor Larsen; Peder Wolkoff; Asger W Nørgaard Journal: J Occup Med Toxicol Date: 2017-12-08 Impact factor: 2.646
Authors: P Duch; A W Nørgaard; J S Hansen; J B Sørli; P Jacobsen; F Lynggard; M Levin; G D Nielsen; P Wolkoff; N E Ebbehøj; S T Larsen Journal: Clin Toxicol (Phila) Date: 2014-05-12 Impact factor: 4.467