Literature DB >> 15007462

An integrated optical oxygen sensor fabricated using rapid-prototyping techniques.

David A Chang-Yen1, Bruce K Gale.   

Abstract

This paper details the design and fabrication of an integrated optical biochemical sensor using a select oxygen-sensitive fluorescent dye, tris(2,2'-bipyridyl) dichlororuthenium(ii) hexahydrate, combined with polymeric waveguides that are fabricated on a glass substrate. The sensor uses evanescent interaction of light confined within the waveguide with the dye that is immobilized on an SU-8 waveguide surface. Adhesion of the dye to the integrated waveguide surface is accomplished using a unique process of spin-coating/electrostatic layer-by-layer formation. The SU-8 waveguide was chemically modified to allow the deposition process. Exposure of the dye molecules to the analyte and subsequent chemical interaction is achieved by directly coupling the fluid channel to the integrated waveguide. The completed sensor was linear in the dissolved oxygen across a wide range of interest and had a sensitivity of 0.6 ppm. A unique fabrication aspect of this sensor is the inherent simplicity of the design, and the resulting rapidity of fabrication, while maintaining a high degree of functionality and flexibility.

Entities:  

Year:  2003        PMID: 15007462     DOI: 10.1039/b305358j

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  6 in total

1.  Simple surface modification techniques for immobilization of biomolecules on SU-8.

Authors:  A Deepu; V V R Sai; S Mukherji
Journal:  J Mater Sci Mater Med       Date:  2008-06-17       Impact factor: 3.896

2.  Study of fluorescence quenching in aluminum-doped ceria nanoparticles: potential molecular probe for dissolved oxygen.

Authors:  N Shehata; K Meehan; D Leber
Journal:  J Fluoresc       Date:  2013-03-03       Impact factor: 2.217

3.  Spatially monitoring oxygen level in 3D microfabricated cell culture systems using optical oxygen sensing beads.

Authors:  Lin Wang; Miguel A Acosta; Jennie B Leach; Rebecca L Carrier
Journal:  Lab Chip       Date:  2013-04-21       Impact factor: 6.799

4.  Photopatternable Polymeric Membranes for Optical Oxygen Sensors.

Authors:  Raghu Ambekar; Jongwon Park; David B Henthorn; Chang-Soo Kim
Journal:  IEEE Sens J       Date:  2009-02-01       Impact factor: 3.301

Review 5.  Optical oxygen sensors for applications in microfluidic cell culture.

Authors:  Samantha M Grist; Lukas Chrostowski; Karen C Cheung
Journal:  Sensors (Basel)       Date:  2010-10-15       Impact factor: 3.576

Review 6.  Recent progress in optical chemical sensors.

Authors:  Hummad Habib Qazi; Abu Bakar bin Mohammad; Muhammad Akram
Journal:  Sensors (Basel)       Date:  2012-11-29       Impact factor: 3.576

  6 in total

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