Literature DB >> 15007340

Clinical deterioration in pediatric asthmatic patients after September 11, 2001.

Anthony M Szema1, Meera Khedkar, Patrick F Maloney, Patricia A Takach, Michael S Nickels, Harshit Patel, Francesmary Modugno, Alan Y Tso, Deborah H Lin.   

Abstract

BACKGROUND: New York City residents were exposed to a variety of inhaled substances after the collapse of the World Trade Center. Exposure to these substances might lead to an increase in asthma severity, with residential distance from Ground Zero predictive of the degree of change.
OBJECTIVE: We sought to assess the effect of the World Trade Center collapse on local pediatric asthmatic patients.
METHODS: We retrospectively reviewed the charts of 205 pediatric patients with established asthma from a clinic in lower Manhattan's Chinatown. Clinical data were obtained for the year before and the year after September 11, 2001. Measurements included numbers of visits, asthma medication prescriptions, oral corticosteroid prescriptions, weekly doses of rescue inhaler, and peak expiratory flow rates. Residential zip codes were used to compare the asthma severity of patients living within and beyond a 5-mile radius of Ground Zero.
RESULTS: After September 11, 2001, these children had more asthma-related clinic visits (P = .002) and received more prescriptions for asthma medications (P = .018). No significant differences in oral steroid or rescue inhaler use were noted. Those living within 5 miles had more clinic visits after September 11, 2001 (P = .013); the increase in clinic visits for patients living more than 5 miles from Ground Zero was not significant. Mean percent predicted peak expiratory flow rates decreased solely for those patients living within 5 miles of Ground Zero during the 3 months after September 11, 2001.
CONCLUSIONS: Asthma severity worsened after September 11, 2001, in pediatric asthmatic patients living near Ground Zero. Residential proximity to Ground Zero was predictive of the degree of decrease in asthma health.

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Year:  2004        PMID: 15007340     DOI: 10.1016/j.jaci.2003.12.015

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


  11 in total

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2.  Emerging exposures and respiratory health: World Trade Center dust.

Authors:  William N Rom; Joan Reibman; Linda Rogers; Michael D Weiden; Beno Oppenheimer; Kenneth Berger; Roberta Goldring; Denise Harrison; David Prezant
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3.  Proposed Iraq/Afghanistan War-Lung Injury (IAW-LI) Clinical Practice Recommendations: National Academy of Sciences' Institute of Medicine Burn Pits Workshop.

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4.  Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust.

Authors:  Michael D Weiden; Natalia Ferrier; Anna Nolan; William N Rom; Ashley Comfort; Jackson Gustave; Rachel Zeig-Owens; Shugi Zheng; Roberta M Goldring; Kenneth I Berger; Kaitlyn Cosenza; Roy Lee; Mayris P Webber; Kerry J Kelly; Thomas K Aldrich; David J Prezant
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5.  Accelerated spirometric decline in New York City firefighters with α₁-antitrypsin deficiency.

Authors:  Gisela I Banauch; Mark Brantly; Gabriel Izbicki; Charles Hall; Alan Shanske; Robert Chavko; Ganesha Santhyadka; Vasilios Christodoulou; Michael D Weiden; David J Prezant
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6.  Trends in respiratory symptoms of firefighters exposed to the world trade center disaster: 2001-2005.

Authors:  Mayris P Webber; Jackson Gustave; Roy Lee; Justin K Niles; Kerry Kelly; Hillel W Cohen; David J Prezant
Journal:  Environ Health Perspect       Date:  2009-02-11       Impact factor: 9.031

7.  Lack of association between estimated World Trade Center plume intensity and respiratory symptoms among New York City residents outside of Lower Manhattan.

Authors:  Robert J Laumbach; Gerald Harris; Howard M Kipen; Panos Georgopoulos; Pamela Shade; Sastry S Isukapalli; Christos Efstathiou; Sandro Galea; David Vlahov; Daniel Wartenberg
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Review 8.  World Trade Center Cough Syndrome and its treatment.

Authors:  David J Prezant
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9.  Asthma and lower respiratory symptoms in New York State employees who responded to the World Trade Center disaster.

Authors:  Matthew P Mauer; Michele L Herdt-Losavio; G Anders Carlson
Journal:  Int Arch Occup Environ Health       Date:  2009-11-05       Impact factor: 3.015

10.  Respiratory and other health effects reported in children exposed to the World Trade Center disaster of 11 September 2001.

Authors:  Pauline A Thomas; Robert Brackbill; Lisa Thalji; Laura DiGrande; Sharon Campolucci; Lorna Thorpe; Kelly Henning
Journal:  Environ Health Perspect       Date:  2008-06-18       Impact factor: 9.031

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