STUDY OBJECTIVES: To investigate the effects of endotracheal suction in volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) with an open suction system (OSS) or a closed suction system (CSS). DESIGN: Randomized comparison. SETTING: Animal research laboratory. PATIENTS: Twelve healthy anesthetized pigs. INTERVENTIONS: The effects of endotracheal suction during VCV and PCV with tidal volume (VT) of 14 mL/kg were compared. A 60-mm inner-diameter endotracheal tube was used. Ten-second suction was performed using OSS and CSS with 12F and 14F catheters connected to - 14 kPa vacuum. MEASUREMENTS AND RESULTS: Thirty minutes after suction in PCV, VT was still decreased by 27% (p < 0.001), compliance (Crs) by 28% (p < 0.001), and PaO(2) by 26% (p < 0.001); PaCO(2) was increased by 42% (p < 0.0001) and venous admixture by 158% (p = 0.003). Suction in VCV affected only Crs (decreased by 23%, p < 0.001) and plateau pressure (increased by 24%, p < 0.001). The initial impairment of gas exchange following suction in VCV was no longer statistically significant after 30 min. CONCLUSIONS: In conclusion, endotracheal suction causes lung collapse leading to impaired gas exchange, an effect that is more severe and persistent in PCV than in VCV.
STUDY OBJECTIVES: To investigate the effects of endotracheal suction in volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) with an open suction system (OSS) or a closed suction system (CSS). DESIGN: Randomized comparison. SETTING: Animal research laboratory. PATIENTS: Twelve healthy anesthetized pigs. INTERVENTIONS: The effects of endotracheal suction during VCV and PCV with tidal volume (VT) of 14 mL/kg were compared. A 60-mm inner-diameter endotracheal tube was used. Ten-second suction was performed using OSS and CSS with 12F and 14F catheters connected to - 14 kPa vacuum. MEASUREMENTS AND RESULTS: Thirty minutes after suction in PCV, VT was still decreased by 27% (p < 0.001), compliance (Crs) by 28% (p < 0.001), and PaO(2) by 26% (p < 0.001); PaCO(2) was increased by 42% (p < 0.0001) and venous admixture by 158% (p = 0.003). Suction in VCV affected only Crs (decreased by 23%, p < 0.001) and plateau pressure (increased by 24%, p < 0.001). The initial impairment of gas exchange following suction in VCV was no longer statistically significant after 30 min. CONCLUSIONS: In conclusion, endotracheal suction causes lung collapse leading to impaired gas exchange, an effect that is more severe and persistent in PCV than in VCV.
Authors: Sophie Lindgren; Helena Odenstedt; Cecilia Olegård; Sören Söndergaard; Stefan Lundin; Ola Stenqvist Journal: Intensive Care Med Date: 2006-10-27 Impact factor: 17.440
Authors: Luciane de Fraga Gomes Martins; Wagner da Silva Naue; Amanda Soares Skueresky; Tanara Bianchi; Alexandre Simões Dias; Luiz Alberto Forgiarini Journal: Indian J Crit Care Med Date: 2019-10