Literature DB >> 15005927

A comparison of two methods of palliation of large bowel obstruction due to irremovable colon cancer.

Richard Johnson1, Ralph Marsh, John Corson, Keith Seymour.   

Abstract

INTRODUCTION: Untreated malignant large bowel obstruction is rapidly fatal. Short-term palliation of symptoms can be achieved by formation of a stoma in those patients for whom resection surgery is inappropriate. In the final months of life, a stoma represents a significant burden for both patients and carers. Palliative endoluminal stenting may therefore be an attractive alternative option for this poor prognostic group. PATIENTS: Thirty-six patients were studied of whom 18 had obstructing left-sided colon cancer relieved by placement of endoluminal stents. These were compared with 18 historical controls with similar clinicopathological features that were treated more conventionally with palliative stoma formation in the same hospital.
RESULTS: Patients in the two groups had similar sex distribution (P = 0.5); however, patients undergoing palliative stoma formation were significantly younger than patients being stented (P = 0.0065). As well as being older, there was a trend towards greater co-morbidities, stent patients having higher ASA grades (P = 0.01). Both groups of patients gained relief of obstructive symptoms. There were no differences in survival (P = 0.5) or in hospital mortality (2 in each group). The median length of palliation is 92 days (42-infinity days) for stenting and 121 days (89-281 days) for palliative stoma formation. Formation of a stoma required a significantly longer stay in ITU (P = 0.003) but total hospital stay was similar.
CONCLUSIONS: As an alternative to palliative surgery, selected patients benefit from colonic endoluminal stenting with relief of obstructive symptoms and no adverse effect on survival. They may be spared the potential problems associated with palliative stoma formation and the morbidity of surgery. Stenting can be offered to the very frail patient who would otherwise be managed conservatively.

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Year:  2004        PMID: 15005927      PMCID: PMC1964159          DOI: 10.1308/003588404322827473

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  18 in total

Review 1.  Self-Expanding Metallic Stents for the Management of Emergency Malignant Large Bowel Obstruction: a Systematic Review.

Authors:  Yasoba Nayanapriya Atukorale; Jody Lynne Church; Benjamin Lee Hoggan; Robyn Sheree Lambert; Stefanie Lynette Gurgacz; Stephen Goodall; Guy J Maddern
Journal:  J Gastrointest Surg       Date:  2016-02       Impact factor: 3.452

2.  Palliative treatment for incurable malignant colorectal obstructions: a meta-analysis.

Authors:  Xiao-Dan Zhao; Bao-Bao Cai; Ri-Sheng Cao; Rui-Hua Shi
Journal:  World J Gastroenterol       Date:  2013-09-07       Impact factor: 5.742

3.  Palliative stent implantation in the treatment of malignant colorectal obstruction.

Authors:  H Ptok; F Meyer; F Marusch; R Steinert; I Gastinger; H Lippert; L Meyer
Journal:  Surg Endosc       Date:  2006-05-11       Impact factor: 4.584

4.  Long-term Postprocedural Outcomes of Palliative Emergency Stenting vs Stoma in Malignant Large-Bowel Obstruction.

Authors:  Jonathan S Abelson; Heather L Yeo; Jialin Mao; Jeffrey W Milsom; Art Sedrakyan
Journal:  JAMA Surg       Date:  2017-05-01       Impact factor: 14.766

5.  Self-Expanding Metallic Stents Versus Surgical Intervention as Palliative Therapy for Obstructive Colorectal Cancer: A Meta-analysis.

Authors:  Hidena Takahashi; Koji Okabayashi; Masashi Tsuruta; Hirotoshi Hasegawa; Masashi Yahagi; Yuko Kitagawa
Journal:  World J Surg       Date:  2015-08       Impact factor: 3.352

6.  Incurable stenosing colorectal carcinoma: endoscopic stent implantation or palliative surgery?

Authors:  Henry Ptok; Frank Marusch; Ralf Steinert; Lutz Meyer; Hans Lippert; Ingo Gastinger
Journal:  World J Surg       Date:  2006-08       Impact factor: 3.352

7.  Managing acute colorectal obstruction by "bridge stenting" to laparoscopic surgery: Our experience.

Authors:  Pierfrancesco Bonfante; Luigi D'Ambra; Stefano Berti; Emilio Falco; Massimo Vittorio Cristoni; Romolo Briglia
Journal:  World J Gastrointest Surg       Date:  2012-12-27

8.  Use of self-expandable stents for obstructive distal and proximal large bowel cancer: a retrospective study in a single centre.

Authors:  Ahmad Al Samaraee; Tarannum Fasih; Mumtaz Hayat
Journal:  J Gastrointest Cancer       Date:  2010-03

9.  Clinical benefits and oncologic equivalence of self-expandable metallic stent insertion for right-sided malignant colonic obstruction.

Authors:  Woong Bae Ji; Jung Myun Kwak; Dong Woo Kang; Han Deok Kwak; Jun Won Um; Sun-Il Lee; Byung-Wook Min; Nak Song Sung; Jin Kim; Seon Hahn Kim
Journal:  Surg Endosc       Date:  2016-05-18       Impact factor: 4.584

Review 10.  Self-expanding metallic stents for relieving malignant colorectal obstruction: a systematic review.

Authors:  Amber M Watt; Ian G Faragher; Tabatha T Griffin; Nicholas A Rieger; Guy J Maddern
Journal:  Ann Surg       Date:  2007-07       Impact factor: 12.969

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