| Literature DB >> 1500354 |
M Matsumoto1, S Matsutani, K Sugita, H Yoshida, F Hayashi, Y Terui, H Nakai, N Uotani, Y Kawamura, K Matsumoto.
Abstract
A novel compound depudecin inducing the flat phenotype of ras- and src- transformed NIH3T3 cells at a concentration of 1 microgram/ml was isolated from the culture broth of Alternaria brassicicola. Based on its spectroscopic characteristics and X-ray crystallographic analysis of its bis-(1S)-(-)-camphanate, the structure of depudecin was determined to be (2R,3S,4S,5E,7S,8S,9R)-2,9- dihydroxy-3,4;7,8-diepoxy-undeca-5,10-diene.Entities:
Mesh：
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Year: 1992 PMID： 1500354 DOI： 10.7164/antibiotics.45.879
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649