Literature DB >> 1500064

Characterization and uses of monoclonal antibody derived against DNA binding domain of the ets family of genes.

N K Bhat1, T S Papas.   

Abstract

A monoclonal antibody recognizing ets proteins from a variety of species has been developed. This antibody recognizes ets1, ets2, erg, and other related proteins. It has a high affinity for the ets1 protein. The epitope for the pan ets mAb consists of about 13 amino acids. This antibody can be used to isolate and characterize new members of ets gene family derived from a c-DNA expression library, as well as to identify other "ets motif" binding proteins.

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Year:  1992        PMID： 1500064     DOI： 10.1089/hyb.1992.11.277

Source DB:  PubMed          Journal:  Hybridoma        ISSN： 0272-457X


  5 in total

1.  A positive regulator of the ribosomal protein gene, beta factor, belongs to the ETS oncoprotein family.

Authors:  T Yoganathan; N K Bhat; B H Sells
Journal:  Biochem J       Date:  1992-10-15       Impact factor: 3.857

2.  Inhibition of EWS-FLI-1 fusion protein with antisense oligodeoxynucleotides.

Authors:  J A Toretsky; Y Connell; L Neckers; N K Bhat
Journal:  J Neurooncol       Date:  1997-01       Impact factor: 4.130

3.  ETS1 suppresses tumorigenicity of human colon cancer cells.

Authors:  H Suzuki; V Romano-Spica; T S Papas; N K Bhat
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205

4.  Identification of a killer cell-specific regulatory element of the mouse perforin gene: an Ets-binding site-homologous motif that interacts with Ets-related proteins.

Authors:  H Koizumi; M F Horta; B S Youn; K C Fu; B S Kwon; J D Young; C C Liu
Journal:  Mol Cell Biol       Date:  1993-11       Impact factor: 4.272

5.  Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription.

Authors:  M F Neurath; E E Max; W Strober
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205
  5 in total

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