Literature DB >> 15000605

Verification of Ir-192 near source dosimetry using GAFCHROMIC film.

Sou-Tung Chiu-Tsao1, Tamara L Duckworth, Neil S Patel, Julianna Pisch, Louis B Harrison.   

Abstract

Intravascular brachytherapy treatments of in-stent restenosis have been performed extensively using Ir-192 ribbon. Task Group 60 of the American Association of Physicists in Medicine (AAPM) recommends a dose reference point at 2 mm from the source center for these treatments. However, it is known that the source can be as close as 0.5 mm to the arterial wall if not centered in the lumen. Therefore, the source dosimetry needs to be characterized at these close distances to accurately determine the amount of dose delivered for noncentered cases. In this paper, we report the verification of the dose distributions around Ir-192 seed sources at radial distances from 0.5 mm to 6 mm using GAFCHROMIC film. We evaluated an Ir-192 single seed source and a train of 6 seeds spaced 1 mm apart enclosed in a nylon ribbon. Each source was placed in a homogeneous solid water phantom directly below a stack of GAFCHROMIC films (MD-55-2). The calibration curve of the lot of films used in the experiment was established for Ir-192 by exposing a set of calibration films, one at a time, to an Ir-192 high dose rate (HDR) source. All films were scanned 5 or more days after exposure with a Lumisys Model 150 microdensitometer. The data were acquired and evaluated using RIT113 (Radiological Imaging Technology) software and analyzed using Excel and IDL (Interactive Data Language) software. Isodose curve plots in the plane containing the source's longitudinal axis and dose rate plots in the radial direction were obtained. For both configurations, the dose rates along the transverse axes agree to within the margin of error with previous Monte Carlo results. The isodose curve plots display hot spots near the seed ends, which is consistent with the leakage of beta particles and electrons from the unsealed seed ends as predicted with Monte Carlo calculations.

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Year:  2004        PMID: 15000605     DOI: 10.1118/1.1637733

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  6 in total

1.  Temperature and hydration effects on absorbance spectra and radiation sensitivity of a radiochromic medium.

Authors:  Alexandra Rink; David F Lewis; Sangya Varma; I Alex Vitkin; David A Jaffray
Journal:  Med Phys       Date:  2008-10       Impact factor: 4.071

2.  Use of new radiochromic devices for peripheral dose measurement: potential in-vivo dosimetry application.

Authors:  S-T Chiu-Tsao; Mf Chan
Journal:  Biomed Imaging Interv J       Date:  2009-10-01

3.  Dosimetric evaluation of a novel high dose rate (HDR) intraluminal / interstitial brachytherapy applicator for gastrointestinal and bladder cancers.

Authors:  Sanaz Hariri Tabrizi; Seyyed Mahmoud Reza Aghamiri; Siamak Najarian; Ramin Jaberi
Journal:  J Appl Clin Med Phys       Date:  2010-12-02       Impact factor: 2.102

4.  Physics-aspects of dose accuracy in high dose rate (HDR) brachytherapy: source dosimetry, treatment planning, equipment performance and in vivo verification techniques.

Authors:  Antony Palmer; David Bradley; Andrew Nisbet
Journal:  J Contemp Brachytherapy       Date:  2012-06-30

5.  A study on the dose distributions in various materials from an Ir-192 HDR brachytherapy source.

Authors:  Shih-Ming Hsu; Chin-Hui Wu; Jeng-Hung Lee; Ya-Ju Hsieh; Chun-Yen Yu; Yi-Jen Liao; Li-Cheng Kuo; Ji-An Liang; David Y C Huang
Journal:  PLoS One       Date:  2012-09-05       Impact factor: 3.240

6.  Suitability of radiochromic films for dosimetry of very-low energy X-rays.

Authors:  Martin A Ebert; Ali H Asad; Salim A Siddiqui
Journal:  J Appl Clin Med Phys       Date:  2009-09-02       Impact factor: 2.102

  6 in total

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