Literature DB >> 15000332

New antidepressants in pregnancy.

Adrienne Einarson1, Gideon Koren.   

Abstract

QUESTION: I have read that fluoxetine is the drug of choice for treating depression during pregnancy. One of my patients, who did not respond to the "old" selective serotonin reuptake inhibitors, is doing well on venlafaxine and is now 6 weeks pregnant. What advice should I give her? ANSWER: Fluoxetine is recommended because to date it has the most evidence of its safety. It is important that women be treated appropriately for depression during pregnancy, and some research on the newer antidepressants, such as venlafaxine, will be useful to you and your patient in making an informed decision regarding treatment.

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Year:  2004        PMID： 15000332      PMCID： PMC2214545     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  10 in total

1.  Pregnancy outcome following gestational exposure to venlafaxine: a multicenter prospective controlled study.

Authors:  A Einarson; B Fatoye; M Sarkar; S V Lavigne; J Brochu; C Chambers; P Mastroiacovo; A Addis; D Matsui; L Schuler; T R Einarson; G Koren
Journal:  Am J Psychiatry       Date:  2001-10       Impact factor: 18.112

2.  Risk-benefit decision making for treatment of depression during pregnancy.

Authors:  K L Wisner; D A Zarin; E S Holmboe; P S Appelbaum; A J Gelenberg; H L Leonard; E Frank
Journal:  Am J Psychiatry       Date:  2000-12       Impact factor: 18.112

3.  Births: preliminary data for 2001.

Authors:  Joyce A Martin; Melissa M Park; Paul D Sutton
Journal:  Natl Vital Stat Rep       Date:  2002-06-06

4.  Pregnancy outcome following maternal use of the new selective serotonin reuptake inhibitors: a prospective controlled multicenter study.

Authors:  N A Kulin; A Pastuszak; S R Sage; B Schick-Boschetto; G Spivey; M Feldkamp; K Ormond; D Matsui; A K Stein-Schechman; L Cook; J Brochu; M Rieder; G Koren
Journal:  JAMA       Date:  1998-02-25       Impact factor: 56.272

5.  Cohort study of depressed mood during pregnancy and after childbirth.

Authors:  J Evans; J Heron; H Francomb; S Oke; J Golding
Journal:  BMJ       Date:  2001-08-04

6.  Abrupt discontinuation of psychotropic drugs during pregnancy: fear of teratogenic risk and impact of counselling.

Authors:  A Einarson; P Selby; G Koren
Journal:  J Psychiatry Neurosci       Date:  2001-01       Impact factor: 6.186

7.  Neurodevelopment of children exposed in utero to antidepressant drugs.

Authors:  I Nulman; J Rovet; D E Stewart; J Wolpin; H A Gardner; J G Theis; N Kulin; G Koren
Journal:  N Engl J Med       Date:  1997-01-23       Impact factor: 91.245

8.  Pregnancy outcome following first-trimester exposure to fluoxetine (Prozac)

Authors:  A Pastuszak; B Schick-Boschetto; C Zuber; M Feldkamp; M Pinelli; S Sihn; A Donnenfeld; M McCormack; M Leen-Mitchell; C Woodland
Journal:  JAMA       Date:  1993-05-05       Impact factor: 56.272

9.  Birth outcomes in pregnant women taking fluoxetine.

Authors:  C D Chambers; K A Johnson; L M Dick; R J Felix; K L Jones
Journal:  N Engl J Med       Date:  1996-10-03       Impact factor: 91.245

10.  A multicentre prospective controlled study to determine the safety of trazodone and nefazodone use during pregnancy.

Authors:  Adrienne Einarson; Lori Bonari; Sharon Voyer-Lavigne; Antonio Addis; Doreen Matsui; Yvette Johnson; Gideon Koren
Journal:  Can J Psychiatry       Date:  2003-03       Impact factor: 4.356
  10 in total
  4 in total

1.  Assessing the effect of Measurement-Based Care depression treatment on HIV medication adherence and health outcomes: rationale and design of the SLAM DUNC Study.

Authors:  Brian W Pence; Bradley N Gaynes; Quinn Williams; Riddhi Modi; Julie Adams; E Byrd Quinlivan; Amy Heine; Nathan Thielman; Michael J Mugavero
Journal:  Contemp Clin Trials       Date:  2012-04-20       Impact factor: 2.226

Review 2.  The safety of newer antidepressants in pregnancy and breastfeeding.

Authors:  Salvatore Gentile
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

3.  Long-term effects of fluoxetine or vehicle administration during pregnancy on behavioral outcomes in guinea pig offspring.

Authors:  Raphael Vartazarmian; Saima Malik; Glen B Baker; Patricia Boksa
Journal:  Psychopharmacology (Berl)       Date:  2004-09-10       Impact factor: 4.530

4.  The role of clomipramine in potentiating the teratogenic effects of caffeine in pregnant rats: a histopathological study.

Authors:  Vahid Nikoui; Sattar Ostadhadi; Nasrin Takzare; Seyyed Mohammad-Ali Nabavi; Mario Giorgi; Azam Bakhtiarian
Journal:  ScientificWorldJournal       Date:  2013-11-04
  4 in total

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